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NCT04747977 · ClinicalTrials.gov registry record · Phase 2
To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Disease
A Phase 2 study, sponsored by Ocular Therapeutix.
- Completed
- Registry status
- Phase 2
- Development phase
- 172
- Enrollment target
NCT04747977: Completed Phase 2 study, sponsored by Ocular Therapeutix.
NCT04747977 is a Phase 2 study that has completed, run by Ocular Therapeutix. The registered enrollment target is 172 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (29% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04747977, a Phase 2 study, has completed, sponsored by Ocular Therapeutix.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 172 participants
- Enrollment target
Study Summary
To assess the efficacy and safety of OTX-DED for the short-term treatment of signs and symptoms of dry eye disease.
Primary Outcome
The primary efficacy endpoint is photographic assessment of bulbar conjunctival hyperemia \[evaluated by the central reading center (CRC)\] in the study eye, change in score from baseline (CFB) at Visit 4 (Day 15). Scoring is from 0 (None) to 4 (Severe) on the CCLRU Grading Scale for Bulbar Conjunctival Hyperemia.
Interventions
- DRUG OTX-DED
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 172 participants |
| Start Date | 2021-02-12 |
| Est. Completion | 2021-09-22 |
| Phase | Phase 2 |
What the finished NCT04747977 record still lists
NCT04747977 is an interventional study that assigns participants to a tested intervention. The registered 172 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (29% higher).
The record links to 0 conditions, and to 1 intervention - of which OTX-DED is the first listed.
NCT04747977 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04747977 about?
NCT04747977 is a clinical study titled "To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Disease". To assess the efficacy and safety of OTX-DED for the short-term treatment of signs and symptoms of dry eye disease.
What is the current status of trial NCT04747977?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 172 participants. The study started on 2021-02-12. Estimated completion is 2021-09-22.
What interventions are being tested in trial NCT04747977?
The interventions under investigation include: OTX-DED (DRUG).
Who is sponsoring clinical trial NCT04747977?
This trial is sponsored by Ocular Therapeutix, which has 20 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04747977's enrollment target sits among peer trials
172 397th of 2000 higher than 1,603 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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