Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04727632 · ClinicalTrials.gov registry record · Early Phase 1
[18F]Fluoroestradiol-PET/CT Companion Imaging Study to the FORESEE Trial
A Early Phase 1 study, sponsored by University of Utah.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 2
- Enrollment target
NCT04727632: Clinical Trial Early Phase 1 study, sponsored by University of Utah.
NCT04727632 is a Early Phase 1 study that was terminated before completion, run by University of Utah. The registered enrollment target is 2 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04727632, a Early Phase 1 study, was terminated before completion, sponsored by University of Utah.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 2 participants
- Enrollment target
Study Summary
This protocol is a companion imaging study that will add FES-PET/CT imaging to the FORESEE trial at HCI. This study will establish the feasibility of using FES-PET/CT imaging to guide therapeutic decision making for functional precision oncology trials. The unique ability of FES-PET/CT to show absence of functional estrogen receptors throughout the entire body may improve confidence among research oncologists that an ER+ metastatic breast cancer patient is truly refractory to hormonal therapies which is a critical determination in the study design of the FORESEE trial.
Primary Outcome
establish proof-of-concept to inform use of FES-PET/CT in future larger precision oncology trials
Interventions
- DRUG [18F]Fluoroestradiol (FES) PET/CT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2021-03-31 |
| Est. Completion | 2024-07-30 |
| Phase | Early Phase 1 |
Why NCT04727632 stopped before completion
NCT04727632 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which [18F]Fluoroestradiol (FES) PET/CT is the first listed.
NCT04727632 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04727632 about?
NCT04727632 is a clinical study titled "[18F]Fluoroestradiol-PET/CT Companion Imaging Study to the FORESEE Trial". This protocol is a companion imaging study that will add FES-PET/CT imaging to the FORESEE trial at HCI. This study will establish the feasibility of using FES-PET/CT imaging to guide therapeutic decision making for functional precision oncology trials. The unique ability of FES-PET/CT to show absen...
What is the current status of trial NCT04727632?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 2 participants. The study started on 2021-03-31. Estimated completion is 2024-07-30.
What interventions are being tested in trial NCT04727632?
The interventions under investigation include: [18F]Fluoroestradiol (FES) PET/CT (DRUG).
Who is sponsoring clinical trial NCT04727632?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04727632's enrollment target sits among peer trials
2 1973rd of 2000 higher than 16 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI