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NCT04726410 · ClinicalTrials.gov registry record · Phase 2
Cold-stored Platelet Early Intervention in TBI
A Phase 2 study, sponsored by Jason Sperry.
- Completed
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
NCT04726410: Completed Phase 2 study, sponsored by Jason Sperry.
NCT04726410 is a Phase 2 study that has completed, run by Jason Sperry. The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04726410, a Phase 2 study, has completed, sponsored by Jason Sperry.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
Study Summary
The Cold Stored Platelet Early Intervention in Traumatic Brain Injury (CriSP-TBI) trial is a proposed 3 year, open label, single center, randomized trial designed to determine the feasibility, efficacy, and safety of urgent release cold stored platelets (CSP) in patients with TBI requiring platelet transfusion. Patients will be randomized to receive either standard care or early infusion of urgent release cold stored platelets (CSP). The proposed pilot study will enroll at the University of Pittsburgh and will enroll approximately 100 patients. The primary outcome for the pilot trial is feasibility, with principal secondary clinical outcome of 6-month Extended Glasgow Outcome Scale (GOS-E).
Primary Outcome
proportion of eligible patients that can be randomized, enrolled, adhere to protocol, and complete follow-up
Interventions
- BIOLOGICAL Cold Stored Platelets
- BIOLOGICAL Standard Care
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2022-03-21 |
| Est. Completion | 2024-05-13 |
| Phase | Phase 2 |
What the finished NCT04726410 record still lists
NCT04726410 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 2 interventions - of which Cold Stored Platelets is the first listed.
NCT04726410 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04726410 about?
NCT04726410 is a clinical study titled "Cold-stored Platelet Early Intervention in TBI". The Cold Stored Platelet Early Intervention in Traumatic Brain Injury (CriSP-TBI) trial is a proposed 3 year, open label, single center, randomized trial designed to determine the feasibility, efficacy, and safety of urgent release cold stored platelets (CSP) in patients with TBI requiring platelet ...
What is the current status of trial NCT04726410?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2022-03-21. Estimated completion is 2024-05-13.
What interventions are being tested in trial NCT04726410?
The interventions under investigation include: Cold Stored Platelets (BIOLOGICAL), Standard Care (BIOLOGICAL).
Who is sponsoring clinical trial NCT04726410?
This trial is sponsored by Jason Sperry, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04726410's enrollment target sits among peer trials
100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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