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NCT04714554 · ClinicalTrials.gov registry record · Phase 1
A Study of the Effects of Erythromycin on the Pharmacokinetics of Relugolix, Estradiol, and Norethindrone in Healthy Postmenopausal Women and on the Pharmacokinetics of Relugolix in Healthy Adult Men
A Phase 1 study, sponsored by Myovant Sciences.
- Completed
- Registry status
- Phase 1
- Development phase
- 43
- Enrollment target
NCT04714554: Completed Phase 1 study, sponsored by Myovant Sciences.
NCT04714554 is a Phase 1 study that has completed, run by Myovant Sciences. The registered enrollment target is 43 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (28% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04714554, a Phase 1 study, has completed, sponsored by Myovant Sciences.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 43 participants
- Enrollment target
Study Summary
This is a two-part, open-label, fixed-sequence, two-period crossover drug interaction study to assess the potential effects of erythromycin on the pharmacokinetics of relugolix, estradiol (E2), and norethindrone (NET) in healthy postmenopausal women (Part 1) and the pharmacokinetics of relugolix in healthy adult men (Part 2).
Interventions
- DRUG Relugolix
- DRUG Erythromycin
- DRUG Relugolix/E2/NETA FDC
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2021-01-06 |
| Est. Completion | 2021-03-29 |
| Phase | Phase 1 |
What the finished NCT04714554 record still lists
NCT04714554 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (28% lower).
The record links to 0 conditions, and to 3 interventions - of which Relugolix is the first listed.
NCT04714554 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04714554 about?
NCT04714554 is a clinical study titled "A Study of the Effects of Erythromycin on the Pharmacokinetics of Relugolix, Estradiol, and Norethindrone in Healthy Postmenopausal Women and on the Pharmacokinetics of Relugolix in Healthy Adult Men". This is a two-part, open-label, fixed-sequence, two-period crossover drug interaction study to assess the potential effects of erythromycin on the pharmacokinetics of relugolix, estradiol (E2), and norethindrone (NET) in healthy postmenopausal women (Part 1) and the pharmacokinetics of relugolix in ...
What is the current status of trial NCT04714554?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 43 participants. The study started on 2021-01-06. Estimated completion is 2021-03-29.
What interventions are being tested in trial NCT04714554?
The interventions under investigation include: Relugolix (DRUG), Erythromycin (DRUG), Relugolix/E2/NETA FDC (DRUG).
Who is sponsoring clinical trial NCT04714554?
This trial is sponsored by Myovant Sciences, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04714554's enrollment target sits among peer trials
43 1100th of 2000 higher than 896 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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