Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04709562 · ClinicalTrials.gov registry record · NA
Clinical Stabilization of Hypercapnia: NIPPV v HVNI
A NA study, sponsored by Vapotherm.
- Completed
- Registry status
- NA
- Development phase
- 68
- Enrollment target
NCT04709562: Completed NA study, sponsored by Vapotherm.
NCT04709562 is a NA study that has completed, run by Vapotherm. The registered enrollment target is 68 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04709562, a NA study, has completed, sponsored by Vapotherm.
- COMPLETED
- Registry status
- NA
- Development phase
- 68 participants
- Enrollment target
Study Summary
This study will evaluate the ability of High Velocity Nasal Insufflation \[HVNI\] to effect ventilation and related physiologic responses in hypercapnic patients when compared to noninvasive positive pressure ventilation \[NIPPV\].
Primary Outcome
Patient's subjective assessment of their dyspnea, rated as a modified Borg score on a scale from 0 to 10. Higher scores indicate a worse outcome.
Interventions
- DEVICE High Velocity Nasal Insufflation (HVNI)
- DEVICE Noninvasive Positive Pressure Ventilation (NIPPV)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2020-11-11 |
| Est. Completion | 2023-06-22 |
| Phase | NA |
What the finished NCT04709562 record still lists
NCT04709562 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which High Velocity Nasal Insufflation (HVNI) is the first listed.
NCT04709562 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04709562 about?
NCT04709562 is a clinical study titled "Clinical Stabilization of Hypercapnia: NIPPV v HVNI". This study will evaluate the ability of High Velocity Nasal Insufflation \[HVNI\] to effect ventilation and related physiologic responses in hypercapnic patients when compared to noninvasive positive pressure ventilation \[NIPPV\].
What is the current status of trial NCT04709562?
This trial is currently completed. It is a NA study. The enrollment target is 68 participants. The study started on 2020-11-11. Estimated completion is 2023-06-22.
What interventions are being tested in trial NCT04709562?
The interventions under investigation include: High Velocity Nasal Insufflation (HVNI) (DEVICE), Noninvasive Positive Pressure Ventilation (NIPPV) (DEVICE).
Who is sponsoring clinical trial NCT04709562?
This trial is sponsored by Vapotherm, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04709562's enrollment target sits among peer trials
68 1133rd of 2000 higher than 862 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02044497 · 68 participants · Phase 4
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Pediatric Surgical Patients
- NCT03779854 · 68 participants · Phase 2
Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant
- NCT03821246 · 68 participants · Phase 2
Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy
- NCT04115514 · 68 participants · Phase 2
Treatment of ARDS With Instilled T3
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI