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NCT04708145 · ClinicalTrials.gov registry record · Phase 4

Long-Term Efficacy and Safety of Intravitreal Aflibercept Injections for the Treatment of Diabetic Retinopathy for Subjects Who Completed the 2-Year PANORAMA Trial

A Phase 4 study, sponsored by Greater Houston Retina Research.

Completed
Registry status
Phase 4
Development phase
41
Enrollment target

NCT04708145: Completed Phase 4 study, sponsored by Greater Houston Retina Research.

NCT04708145 is a Phase 4 study that has completed, run by Greater Houston Retina Research. The registered enrollment target is 41 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04708145, a Phase 4 study, has completed, sponsored by Greater Houston Retina Research.

COMPLETED
Registry status
Phase 4
Development phase
41 participants
Enrollment target

Study Summary

The VOYAGE trial will assess diabetic retinopathy severity scale (DRSS) levels, through 112 weeks, while being managed with aflibercept as needed, among subjects who completed the 2-year PANORAMA trial (VGFTe-OD-1411) and were treated in a clinical setting prior to joining the VOYAGE study.

Primary Outcome

Proportion of subjects achieving a DRSS level of 43 or less in the VOYAGE study.

Interventions

  • DRUG Aflibercept Injection

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2021-06-01
Est. Completion 2024-07-31
Phase Phase 4
Greater Houston Retina Research

8 total trials

What the finished NCT04708145 record still lists

NCT04708145 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which Aflibercept Injection is the first listed.

NCT04708145 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04708145 about?

NCT04708145 is a clinical study titled "Long-Term Efficacy and Safety of Intravitreal Aflibercept Injections for the Treatment of Diabetic Retinopathy for Subjects Who Completed the 2-Year PANORAMA Trial". The VOYAGE trial will assess diabetic retinopathy severity scale (DRSS) levels, through 112 weeks, while being managed with aflibercept as needed, among subjects who completed the 2-year PANORAMA trial (VGFTe-OD-1411) and were treated in a clinical setting prior to joining the VOYAGE study.

What is the current status of trial NCT04708145?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 41 participants. The study started on 2021-06-01. Estimated completion is 2024-07-31.

What interventions are being tested in trial NCT04708145?

The interventions under investigation include: Aflibercept Injection (DRUG).

Who is sponsoring clinical trial NCT04708145?

This trial is sponsored by Greater Houston Retina Research, which has 8 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04708145's enrollment target sits among peer trials

41 1390th of 2000 higher than 604 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04708145, the US trial registry maintained by the National Library of Medicine. NCT04708145 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.