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NCT04705922 · ClinicalTrials.gov registry record · Phase 1
Relative Bioavailability Study and Food Effect Study of TT-00420 (Tinengotinib) Capsule and Tablet Formulations in Healthy Volunteers
A Phase 1 study, sponsored by TransThera Sciences (Nanjing).
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT04705922: Completed Phase 1 study, sponsored by TransThera Sciences (Nanjing).
NCT04705922 is a Phase 1 study that has completed, run by TransThera Sciences (Nanjing). The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04705922, a Phase 1 study, has completed, sponsored by TransThera Sciences (Nanjing).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
This study is an open-label, 3-way crossover randomized study in adult healthy volunteers to evaluate the relative bioavailability of TT-00420 tablet and capsule formulations and to evaluate food effect on the pharmacokinetics of TT-00420 tablet.
Primary Outcome
Blood samples will be collected at indicated time points for pharmacokinetic analysis of TT-00420.
Interventions
- DRUG TT-00420 Capsule
- DRUG TT-00420 Tablet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2020-12-29 |
| Est. Completion | 2021-07-23 |
| Phase | Phase 1 |
What the finished NCT04705922 record still lists
NCT04705922 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 2 interventions - of which TT-00420 Capsule is the first listed.
NCT04705922 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04705922 about?
NCT04705922 is a clinical study titled "Relative Bioavailability Study and Food Effect Study of TT-00420 (Tinengotinib) Capsule and Tablet Formulations in Healthy Volunteers". This study is an open-label, 3-way crossover randomized study in adult healthy volunteers to evaluate the relative bioavailability of TT-00420 tablet and capsule formulations and to evaluate food effect on the pharmacokinetics of TT-00420 tablet.
What is the current status of trial NCT04705922?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2020-12-29. Estimated completion is 2021-07-23.
What interventions are being tested in trial NCT04705922?
The interventions under investigation include: TT-00420 Capsule (DRUG), TT-00420 Tablet (DRUG).
Who is sponsoring clinical trial NCT04705922?
This trial is sponsored by TransThera Sciences (Nanjing), which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04705922's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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