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NCT04696380 · ClinicalTrials.gov registry record · Phase 2
Do Flavors Increase the Addiction Potential of Nicotine?
A Phase 2 study, sponsored by University of Vermont.
- Completed
- Registry status
- Phase 2
- Development phase
- 19
- Enrollment target
NCT04696380 is a Phase 2 study that has completed, run by University of Vermont. The registered enrollment target is 19 participants.
The verdict
NCT04696380, a Phase 2 study, has completed, sponsored by University of Vermont.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 19 participants
- Enrollment target
Study Summary
The FDA has concluded that flavors (e.g. menthol) are associated with greater addiction potential in tobacco cigarettes (Gottlieb March 13, 2019). Whether the same is true for e-cigarettes and non-menthol flavors is unclear and our study should help answer this question. Our major hypothesis is that the pharmacological effect of nicotine to induce addiction will be greater with use of a preferred e-cigarette flavor than with use of a non-preferred flavor. The pharmacological effect will be measured by how much a larger nicotine dose increases addiction potential compared to a smaller dose.
Interventions
- DRUG Nicotine
- DEVICE JUUL e-cigarette
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2021-03-01 |
| Est. Completion | 2021-08-31 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04696380
The ClinicalTrials.gov registry entry for NCT04696380 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Vermont, which has 162 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Nicotine is the first listed.
NCT04696380 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04696380 about?
NCT04696380 is a clinical study titled "Do Flavors Increase the Addiction Potential of Nicotine?". The FDA has concluded that flavors (e.g. menthol) are associated with greater addiction potential in tobacco cigarettes (Gottlieb March 13, 2019). Whether the same is true for e-cigarettes and non-menthol flavors is unclear and our study should help answer this question. Our major hypothesis is tha...
What is the current status of trial NCT04696380?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 2021-03-01. Estimated completion is 2021-08-31.
What interventions are being tested in trial NCT04696380?
The interventions under investigation include: Nicotine (DRUG), JUUL e-cigarette (DEVICE).
Who is sponsoring clinical trial NCT04696380?
This trial is sponsored by University of Vermont, which has 162 total clinical trials registered on ClinicalTrials.gov.
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