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NCT04669743 · ClinicalTrials.gov registry record · NA
Innate Immunity in Ozone-induced Airway Inflammation in COPD
A NA study, sponsored by University of California, San Francisco.
- Active
- Registry status
- NA
- Development phase
- 72
- Enrollment target
NCT04669743: Active NA study, sponsored by University of California, San Francisco.
NCT04669743 is a NA study that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 72 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04669743, a NA study, is active but no longer recruiting, sponsored by University of California, San Francisco.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 72 participants
- Enrollment target
Study Summary
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. Patients with COPD are routinely exposed to indoor and outdoor air pollution, which appears to cause escalation of their respiratory symptoms, a process called exacerbation, with resulting need to seek medical attention. This research plan proposes to evaluate the impact of lung immune cells in susceptibility to develop exacerbation through an experimental model of inhalational exposure using ambient levels of a component of air pollution (ozone) in COPD patients and longitudinal sampling of their lung immune cells.
Primary Outcome
Number of alveolar macrophages (AM) measured by flow cytometry (both absolute numbers and relative percentage of cells)
Interventions
- OTHER Ozone exposure
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2016-04-07 |
| Est. Completion | 2030-12-31 |
| Phase | NA |
What the registry record for NCT04669743 still lists
NCT04669743 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which Ozone exposure is the first listed.
NCT04669743 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04669743 about?
NCT04669743 is a clinical study titled "Innate Immunity in Ozone-induced Airway Inflammation in COPD". Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. Patients with COPD are routinely exposed to indoor and outdoor air pollution, which appears to cause escalation of their respiratory symptoms, a process called exacerbation, with resulting need to ...
What is the current status of trial NCT04669743?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 72 participants. The study started on 2016-04-07. Estimated completion is 2030-12-31.
What interventions are being tested in trial NCT04669743?
The interventions under investigation include: Ozone exposure (OTHER).
Who is sponsoring clinical trial NCT04669743?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04669743's enrollment target sits among peer trials
72 1089th of 2000 higher than 899 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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