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NCT04649541 · ClinicalTrials.gov registry record · Phase 1
Study of the Safety, Tolerability, and PK of MRX-8 Administered Intravenously to HVs in SAD and MAD Cohorts
A Phase 1 study, sponsored by MicuRx.
- Completed
- Registry status
- Phase 1
- Development phase
- 69
- Enrollment target
NCT04649541: Completed Phase 1 study, sponsored by MicuRx.
NCT04649541 is a Phase 1 study that has completed, run by MicuRx. The registered enrollment target is 69 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (15% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04649541, a Phase 1 study, has completed, sponsored by MicuRx.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 69 participants
- Enrollment target
Study Summary
This Phase 1 study is designed to assess the safety and tolerability of single and multiple intravenous (IV) doses of MRX-8, to assess the pharmacokinetics of MRX-8 and its primary metabolite following single and multiple IV doses, and to measure the elimination of MRX-8 and its metabolite in urine.
Primary Outcome
Symptoms reported by subjects.
Interventions
- DRUG Placebo
- DRUG MRX-8
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 69 participants |
| Start Date | 2020-11-29 |
| Est. Completion | 2021-12-01 |
| Phase | Phase 1 |
What the finished NCT04649541 record still lists
NCT04649541 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 69 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (15% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04649541 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04649541 about?
NCT04649541 is a clinical study titled "Study of the Safety, Tolerability, and PK of MRX-8 Administered Intravenously to HVs in SAD and MAD Cohorts". This Phase 1 study is designed to assess the safety and tolerability of single and multiple intravenous (IV) doses of MRX-8, to assess the pharmacokinetics of MRX-8 and its primary metabolite following single and multiple IV doses, and to measure the elimination of MRX-8 and its metabolite in urine.
What is the current status of trial NCT04649541?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 69 participants. The study started on 2020-11-29. Estimated completion is 2021-12-01.
What interventions are being tested in trial NCT04649541?
The interventions under investigation include: Placebo (DRUG), MRX-8 (DRUG).
Who is sponsoring clinical trial NCT04649541?
This trial is sponsored by MicuRx, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04649541's enrollment target sits among peer trials
69 774th of 2000 higher than 1,225 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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