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NCT04646239 · ClinicalTrials.gov registry record

Biomarkers of Trained Immunity Following MMR Vaccination

A clinical trial, sponsored by Washington University School of Medicine.

Completed
Registry status
96
Enrollment target

NCT04646239 is a clinical trial that has completed, run by Washington University School of Medicine. The registered enrollment target is 96 participants.

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The verdict

NCT04646239 has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
96 participants
Enrollment target

Study Summary

This is a substudy of NCT04333732. The goal of this sub-study is to identify and characterize biomarkers of trained immunity by measuring, in vitro, immune responses to heterologous products, especially viral associated products, in the MMR vaccinated compared placebo groups. All participants are randomly assigned to MMR or placebo injection at baseline, followed by SARS-CoV-2 specific vaccination. Blood is drawn around 60 to 90 days after the last SARS-CoV-2 specific vaccine injection.

Interventions

  • DIAGNOSTIC_TEST Heterologous stimuli
  • DIAGNOSTIC_TEST Neutralization assay

Trial Details

FieldValue
Enrollment Target 96 participants
Start Date 2020-12-17
Est. Completion 2021-06-28

What the Registry Record Tells You About NCT04646239

The ClinicalTrials.gov registry entry for NCT04646239 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 96 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Heterologous stimuli is the first listed.

NCT04646239 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04646239 about?

NCT04646239 is a clinical study titled "Biomarkers of Trained Immunity Following MMR Vaccination". This is a substudy of NCT04333732. The goal of this sub-study is to identify and characterize biomarkers of trained immunity by measuring, in vitro, immune responses to heterologous products, especially viral associated products, in the MMR vaccinated compared placebo groups. All participants are r...

What is the current status of trial NCT04646239?

This trial is currently completed. The enrollment target is 96 participants. The study started on 2020-12-17. Estimated completion is 2021-06-28.

What interventions are being tested in trial NCT04646239?

The interventions under investigation include: Heterologous stimuli (DIAGNOSTIC_TEST), Neutralization assay (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT04646239?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.