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NCT04640272 · ClinicalTrials.gov registry record · Phase 2

A Multi-Center, Open Label, Extension Study Assessing the Efficacy and Safety of Additional Intravitreal Injections of RBM-007 in Subjects With Wet Age-related Macular Degeneration

A Phase 2 study, sponsored by Ribomic USA.

Completed
Registry status
Phase 2
Development phase
40
Enrollment target

NCT04640272: Completed Phase 2 study, sponsored by Ribomic USA.

NCT04640272 is a Phase 2 study that has completed, run by Ribomic USA. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04640272, a Phase 2 study, has completed, sponsored by Ribomic USA.

COMPLETED
Registry status
Phase 2
Development phase
40 participants
Enrollment target

Study Summary

This is a multi-center, open label, extension study of NCT04200248 assessing the efficacy and safety of additional intravitreal injections of RBM-007 in subjects with wet age-related macular degeneration.

Primary Outcome

Mean change in Best Corrected Visual Acuity from Baseline

Interventions

  • DRUG RBM-007

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2020-11-03
Est. Completion 2021-12-22
Phase Phase 2
Ribomic USA

3 total trials

What the finished NCT04640272 record still lists

NCT04640272 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).

The record links to 0 conditions, and to 1 intervention - of which RBM-007 is the first listed.

NCT04640272 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04640272 about?

NCT04640272 is a clinical study titled "A Multi-Center, Open Label, Extension Study Assessing the Efficacy and Safety of Additional Intravitreal Injections of RBM-007 in Subjects With Wet Age-related Macular Degeneration". This is a multi-center, open label, extension study of NCT04200248 assessing the efficacy and safety of additional intravitreal injections of RBM-007 in subjects with wet age-related macular degeneration.

What is the current status of trial NCT04640272?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2020-11-03. Estimated completion is 2021-12-22.

What interventions are being tested in trial NCT04640272?

The interventions under investigation include: RBM-007 (DRUG).

Who is sponsoring clinical trial NCT04640272?

This trial is sponsored by Ribomic USA, which has 3 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04640272's enrollment target sits among peer trials

40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04640272, the US trial registry maintained by the National Library of Medicine. NCT04640272 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.