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NCT04632992 · ClinicalTrials.gov registry record · Phase 2

A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response

A Phase 2 study, sponsored by Genentech.

Completed
Registry status
Phase 2
Development phase
252
Enrollment target

NCT04632992 is a Phase 2 study that has completed, run by Genentech. The registered enrollment target is 252 participants.

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The verdict

NCT04632992, a Phase 2 study, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 2
Development phase
252 participants
Enrollment target

Study Summary

This is a Phase II, multicenter, non-randomized, open-label, multi-arm study designed to evaluate the safety and efficacy of targeted therapies as single agents or in rational, specified combinations in participants with advanced unresectable or metastatic solid tumors determined to harbor specific biomarkers. Patients will be enrolled based on local testing performed at a Clinical Laboratory Improvement Amendments (CLIA)-certified or equivalently accredited diagnostic laboratory. The multi-arm structure of the MyTACTIC study allows patients with solid tumors to be treated with a drug or drug regimen tailored to their biomarker identified at screening.

Interventions

  • DRUG Atezolizumab
  • DRUG Ipatasertib
  • DRUG Inavolisib
  • DRUG Alectinib
  • DRUG Entrectinib

Trial Details

FieldValue
Enrollment Target 252 participants
Start Date 2021-01-13
Est. Completion 2024-02-27
Phase Phase 2

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT04632992

The ClinicalTrials.gov registry entry for NCT04632992 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 252 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Atezolizumab is the first listed.

NCT04632992 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04632992 about?

NCT04632992 is a clinical study titled "A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response". This is a Phase II, multicenter, non-randomized, open-label, multi-arm study designed to evaluate the safety and efficacy of targeted therapies as single agents or in rational, specified combinations in participants with advanced unresectable or metastatic solid tumors determined to harbor specific ...

What is the current status of trial NCT04632992?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 252 participants. The study started on 2021-01-13. Estimated completion is 2024-02-27.

What interventions are being tested in trial NCT04632992?

The interventions under investigation include: Atezolizumab (DRUG), Ipatasertib (DRUG), Inavolisib (DRUG), Alectinib (DRUG), Entrectinib (DRUG).

Who is sponsoring clinical trial NCT04632992?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.