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NCT04626284 · ClinicalTrials.gov registry record · NA
Safety and Effectiveness of NRP for DCD Heart Transplantation
A NA study, sponsored by University of Nebraska.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT04626284: Completed NA study, sponsored by University of Nebraska.
NCT04626284 is a NA study that has completed, run by University of Nebraska. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04626284, a NA study, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
This is a prospective, observational, pilot trial to evaluate the feasibility of heart transplantation using normothermic regional perfusion (NRP) donation after donor circulatory death (DCD). Normothermic regional perfusion utilizes Extracorporeal Membrane Oxygenation (ECMO) or cardiopulmonary bypass to reperfuse the heart and other organs in situ after isolation and ligation of the cerebral vessels. In situ resuscitation of the heart has the added advantage of allowing full hemodynamic and echocardiographic assessment of the donor heart prior to final acceptance for transplantation without the imminent danger of ongoing warm ischemia.
Primary Outcome
Ratio of successful heart transplants using grafts obtained from DCD donors using NRO to the total number of DCD donors in whom NRP was used to procure an organ
Interventions
- PROCEDURE Heart Transplantation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2021-01-03 |
| Est. Completion | 2022-04-08 |
| Phase | NA |
What the finished NCT04626284 record still lists
NCT04626284 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Heart Transplantation is the first listed.
NCT04626284 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04626284 about?
NCT04626284 is a clinical study titled "Safety and Effectiveness of NRP for DCD Heart Transplantation". This is a prospective, observational, pilot trial to evaluate the feasibility of heart transplantation using normothermic regional perfusion (NRP) donation after donor circulatory death (DCD). Normothermic regional perfusion utilizes Extracorporeal Membrane Oxygenation (ECMO) or cardiopulmonary bypa...
What is the current status of trial NCT04626284?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2021-01-03. Estimated completion is 2022-04-08.
What interventions are being tested in trial NCT04626284?
The interventions under investigation include: Heart Transplantation (PROCEDURE).
Who is sponsoring clinical trial NCT04626284?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04626284's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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