Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04623710 · ClinicalTrials.gov registry record · Phase 1

Study of ALXN2050 in Participants With Renal Impairment

A Phase 1 study, sponsored by Alexion Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target

NCT04623710: Completed Phase 1 study, sponsored by Alexion Pharmaceuticals.

NCT04623710 is a Phase 1 study that has completed, run by Alexion Pharmaceuticals. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04623710, a Phase 1 study, has completed, sponsored by Alexion Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target

Study Summary

This study will investigate the impact of impaired renal function on the plasma pharmacokinetics of ALXN2050 in order to provide dosing recommendations for future indications in individuals with impaired renal function.

Interventions

  • DRUG ALXN2050

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2021-07-08
Est. Completion 2022-03-21
Phase Phase 1
Alexion Pharmaceuticals

162 total trials

What the finished NCT04623710 record still lists

NCT04623710 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).

The record links to 0 conditions, and to 1 intervention - of which ALXN2050 is the first listed.

NCT04623710 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04623710 about?

NCT04623710 is a clinical study titled "Study of ALXN2050 in Participants With Renal Impairment". This study will investigate the impact of impaired renal function on the plasma pharmacokinetics of ALXN2050 in order to provide dosing recommendations for future indications in individuals with impaired renal function.

What is the current status of trial NCT04623710?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2021-07-08. Estimated completion is 2022-03-21.

What interventions are being tested in trial NCT04623710?

The interventions under investigation include: ALXN2050 (DRUG).

Who is sponsoring clinical trial NCT04623710?

This trial is sponsored by Alexion Pharmaceuticals, which has 162 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04623710's enrollment target sits among peer trials

40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01306019 · 40 participants · Phase 1

    Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

  • NCT01608152 · 40 participants

    Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors

  • NCT01668082 · 40 participants · NA

    An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection

  • NCT02015013 · 40 participants · Phase 2

    Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04623710, the US trial registry maintained by the National Library of Medicine. NCT04623710 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.