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NCT04620239 · ClinicalTrials.gov registry record · Phase 3

ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study

A Phase 3 study of Transitional Cell Cancer of Renal Pelvis and Ureter, sponsored by Steba Biotech S.A..

Recruiting
Registry status
Phase 3
Development phase
100
Enrollment target
18
Study locations

NCT04620239 is a Phase 3 study of Transitional Cell Cancer of Renal Pelvis and Ureter that is actively recruiting participants, run by Steba Biotech S.A.. The registered enrollment target is 100 participants. The trial reports 18 study locations across 10 states.

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The verdict

NCT04620239, a Phase 3 study of Transitional Cell Cancer of Renal Pelvis and Ureter, is actively recruiting participants, sponsored by Steba Biotech S.A..

RECRUITING
Registry status
Phase 3
Development phase
100 participants
Enrollment target
18
Study locations

Study Summary

This is a phase 3, open label, single arm study of padeliporfin in the treatment of Upper Tract Urothelial Carcinoma (UTUC). The ENLIGHTED study will recruit patients with low-grade non-invasive upper tract urothelial carcinoma in either the kidney or the ureter. Patients will be treated with padeliporfin VTP in two phases: an Induction Treatment Phase and a Maintenance Treatment Phase and will be followed up for up to an additional 48 months in the long term (non intervention) follow up phase with the specific duration depending on the patient's response to treatment

Interventions

  • DRUG padeliporfin VTP

Study Locations (18)

Other

  • CHU de Lille - Hopital Claude Huriez - Lille
  • HCL Hopital Edouard Herriot - Lyon
  • Universitaetsklinikum Tuebingen - Tübingen
  • Sheba Medical Center - Ramat Gan
  • Hospital Universitario de A Coruña - A Coruña
  • Hospital Universitario Vall d'Hebron - Barcelona

California

  • University of California - Irvine Medical Center - Irvine
  • Keck School of Medicine at USC Medical Center - Los Angeles

New York

  • Albany Medical College - Albany
  • Memorial Sloan Kettering Cancer Center - New York

South Carolina

  • Medical University of South Carolina (MUSC) - Charleston
  • Carolina Urologic Research Center - Myrtle Beach

Georgia

  • Emory University Hospital - Atlanta

Maryland

  • The Johns Hopkins Hospital, The Sidney Kimmel Cancer Center - Baltimore

Ohio

  • The Ohio State University (OSU) - Columbus

Pennsylvania

  • The Pennsylvania State University (Penn State) Milton S. Hershey Medical Center - Hershey

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2021-03-22
Est. Completion 2029-01-25
Phase Phase 3

Sponsor

Steba Biotech S.A.

4 total trials

What the Registry Record Tells You About NCT04620239

The ClinicalTrials.gov registry entry for NCT04620239 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Steba Biotech S.A., which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Transitional Cell Cancer of Renal Pelvis and Ureter appearing as the primary indexed condition, and to 1 intervention - of which padeliporfin VTP is the first listed.

NCT04620239 reports 18 study locations spanning 10 distinct geographic areas - top geographies include Other, California, New York.

Frequently Asked Questions

What is clinical trial NCT04620239 about?

NCT04620239 is a clinical study titled "ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study". This is a phase 3, open label, single arm study of padeliporfin in the treatment of Upper Tract Urothelial Carcinoma (UTUC). The ENLIGHTED study will recruit patients with low-grade non-invasive upper tract urothelial carcinoma in either the kidney or the ureter. Patients will be treated with padeli...

What is the current status of trial NCT04620239?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 100 participants. The study started on 2021-03-22. Estimated completion is 2029-01-25.

What conditions does trial NCT04620239 study?

This clinical trial studies the following conditions: Transitional Cell Cancer of Renal Pelvis and Ureter.

What interventions are being tested in trial NCT04620239?

The interventions under investigation include: padeliporfin VTP (DRUG).

Who is sponsoring clinical trial NCT04620239?

This trial is sponsored by Steba Biotech S.A., which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04620239 being conducted?

This trial has 18 study locations across California, Georgia, Maryland, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.