Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04603469 · ClinicalTrials.gov registry record
Hypotension in Children With Down Syndrome With Anesthesia Induction
A clinical trial, sponsored by Baylor College of Medicine.
- Completed
- Registry status
- 45
- Enrollment target
NCT04603469: Completed study, sponsored by Baylor College of Medicine.
NCT04603469 is a clinical trial that has completed, run by Baylor College of Medicine. The registered enrollment target is 45 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04603469 has completed, sponsored by Baylor College of Medicine.
- COMPLETED
- Registry status
- 45 participants
- Enrollment target
Study Summary
Children generally undergo induction of anesthesia by inhalation of sevoflurane. Children with Down Syndrome experience bradycardia with induction of anesthesia using sevoflurane. It is unknown if this bradycardia is isolate or results in hypotension, thus requiring treatment. Isolate bradycardia without hypotension does not require treatment and should be avoided as many of these patients have underlying cardiac anomalies.
Primary Outcome
non invasive blood pressure during induction (systolic, diastolic and Mean pressures)
Interventions
- OTHER Non invasive blood pressure
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2021-05-26 |
| Est. Completion | 2021-10-28 |
What the finished NCT04603469 record still lists
NCT04603469 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 45 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Non invasive blood pressure is the first listed.
NCT04603469 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04603469 about?
NCT04603469 is a clinical study titled "Hypotension in Children With Down Syndrome With Anesthesia Induction". Children generally undergo induction of anesthesia by inhalation of sevoflurane. Children with Down Syndrome experience bradycardia with induction of anesthesia using sevoflurane. It is unknown if this bradycardia is isolate or results in hypotension, thus requiring treatment. Isolate bradycardia wi...
What is the current status of trial NCT04603469?
This trial is currently completed. The enrollment target is 45 participants. The study started on 2021-05-26. Estimated completion is 2021-10-28.
What interventions are being tested in trial NCT04603469?
The interventions under investigation include: Non invasive blood pressure (OTHER).
Who is sponsoring clinical trial NCT04603469?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00804154 · 45 participants · Phase 1
Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer
- NCT01851694 · 45 participants · NA
Beta-cell Response to Incretin Hormones in Cystic Fibrosis
- NCT02896335 · 45 participants · Phase 2
Palbociclib and Pembrolizumab In Central Nervous System Metastases
- NCT03454035 · 45 participants · Phase 1
Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI