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NCT04600115 · ClinicalTrials.gov registry record · Early Phase 1
New MRI Methods Applied to Heart Failure With Preserved Ejection Fraction (HFpEF)
A Early Phase 1 study, sponsored by University of Utah.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 100
- Enrollment target
NCT04600115: Recruiting Early Phase 1 study, sponsored by University of Utah.
NCT04600115 is a Early Phase 1 study that is actively recruiting participants, run by University of Utah. The registered enrollment target is 100 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (89% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04600115, a Early Phase 1 study, is actively recruiting participants, sponsored by University of Utah.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 100 participants
- Enrollment target
Study Summary
This study's main specific aims are; 1. To develop robust acquisition and reconstruction methods specifically for the study of microvascular cardiac remodeling with MRI which will include very innovative quantitative perfusion methods, as well as fibrosis quantification, longitudinal strain, and phase contrast imaging for flow. 2. Test the new methods for identifying the clinical task of characterizing HFpEF.
Primary Outcome
Myocardial perfusion measured with Magnetic Resonance Imaging (MRI) at rest and vasodilation
Interventions
- DEVICE MRI
- DRUG Regadenoson
- DRUG Adenosine
- DRUG O-15 labeled radioactive water
- DEVICE PET Imaging
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2017-03-03 |
| Est. Completion | 2027-03-03 |
| Phase | Early Phase 1 |
What NCT04600115 shows while recruiting
NCT04600115 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (89% higher).
The record links to 0 conditions, and to 5 interventions - of which MRI is the first listed.
NCT04600115 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04600115 about?
NCT04600115 is a clinical study titled "New MRI Methods Applied to Heart Failure With Preserved Ejection Fraction (HFpEF)". This study's main specific aims are; 1. To develop robust acquisition and reconstruction methods specifically for the study of microvascular cardiac remodeling with MRI which will include very innovative quantitative perfusion methods, as well as fibrosis quantification, longitudinal strain, and ph...
What is the current status of trial NCT04600115?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 100 participants. The study started on 2017-03-03. Estimated completion is 2027-03-03.
What interventions are being tested in trial NCT04600115?
The interventions under investigation include: MRI (DEVICE), Regadenoson (DRUG), Adenosine (DRUG), O-15 labeled radioactive water (DRUG), PET Imaging (DEVICE).
Who is sponsoring clinical trial NCT04600115?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04600115's enrollment target sits among peer trials
100 184th of 2000 higher than 1,783 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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