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NCT04598542 · ClinicalTrials.gov registry record · Phase 1

Drug-Drug Interaction Study of Lorecivivint and Triamcinolone Acetonide in Healthy Volunteers

A Phase 1 study, sponsored by Biosplice Therapeutics.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target

NCT04598542 is a Phase 1 study that has completed, run by Biosplice Therapeutics. The registered enrollment target is 40 participants.

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The verdict

NCT04598542, a Phase 1 study, has completed, sponsored by Biosplice Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target

Study Summary

This study will be an open-label, parallel-arm study to determine if a prior intra-articular (IA) injection of lorecivivint (LOR) affects the safety, tolerability, and/or pharmacokinetics (PK) of a subsequent IA injection of the corticosteroid triamcinolone acetonide (TA) into the same knee, and to determine if a prior IA injection of TA affects the safety or tolerability of a subsequent IA injection of LOR into the same knee.

Interventions

  • DRUG Lorecivivint (LOR)
  • DRUG Triamcinolone acetonide (TA)

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2020-10-13
Est. Completion 2020-12-22
Phase Phase 1

Sponsor

Biosplice Therapeutics

20 total trials

What the Registry Record Tells You About NCT04598542

The ClinicalTrials.gov registry entry for NCT04598542 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Biosplice Therapeutics, which has 20 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Lorecivivint (LOR) is the first listed.

NCT04598542 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04598542 about?

NCT04598542 is a clinical study titled "Drug-Drug Interaction Study of Lorecivivint and Triamcinolone Acetonide in Healthy Volunteers". This study will be an open-label, parallel-arm study to determine if a prior intra-articular (IA) injection of lorecivivint (LOR) affects the safety, tolerability, and/or pharmacokinetics (PK) of a subsequent IA injection of the corticosteroid triamcinolone acetonide (TA) into the same knee, and to ...

What is the current status of trial NCT04598542?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2020-10-13. Estimated completion is 2020-12-22.

What interventions are being tested in trial NCT04598542?

The interventions under investigation include: Lorecivivint (LOR) (DRUG), Triamcinolone acetonide (TA) (DRUG).

Who is sponsoring clinical trial NCT04598542?

This trial is sponsored by Biosplice Therapeutics, which has 20 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.