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NCT04587024 · ClinicalTrials.gov registry record · NA
A Study of mDOT for Immunosuppressant Adherence in Solid Organ Transplant Recipients
A NA study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 75
- Enrollment target
NCT04587024: Completed NA study, sponsored by Johns Hopkins University.
NCT04587024 is a NA study that has completed, run by Johns Hopkins University. The registered enrollment target is 75 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04587024, a NA study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
Study Summary
In solid organ transplant recipients, poor adherence to immunosuppressant medications carries the risk of graft rejection (needing a new transplant), post-transplant complications, and increased healthcare costs. Additionally, nonadherence to immunosuppressant medications is imperative to short- and long-term outcomes. The rate of nonadherence in this population varies vastly. Because of lacking objective and accurate nonadherence measurements, both to immunosuppressant drugs and medical indications, the true implications and prevalence of nonadherence is not yet well understood. Therefore, investigators believe that mobile health (mHealth) technology has the potential to allow clinicians and researchers to more comprehensively address and understand nonadherence in solid organ transplant recipients. The aim of this study is to conduct a randomized control trial to compare medication adherence among liver and kidney transplant patients who use the mHealth system against controls who do not.
Primary Outcome
To compare medication adherence of solid organ transplant recipients, specifically liver and kidney transplants, using the mobile DOT (mDOT) application (i.e., intervention) to those who did not use the mDOT application (i.e., control). The investigators will compare medication adherence between intervention and control arms using the Medication Level Variability Index (MLVI), a validated measure of adherence derived from the standard deviation of measured drug levels. The investigators will loo
Interventions
- OTHER standard of care
- OTHER mHealth intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2020-11-20 |
| Est. Completion | 2023-08-31 |
| Phase | NA |
What the finished NCT04587024 record still lists
NCT04587024 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which standard of care is the first listed.
NCT04587024 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04587024 about?
NCT04587024 is a clinical study titled "A Study of mDOT for Immunosuppressant Adherence in Solid Organ Transplant Recipients". In solid organ transplant recipients, poor adherence to immunosuppressant medications carries the risk of graft rejection (needing a new transplant), post-transplant complications, and increased healthcare costs. Additionally, nonadherence to immunosuppressant medications is imperative to short- and...
What is the current status of trial NCT04587024?
This trial is currently completed. It is a NA study. The enrollment target is 75 participants. The study started on 2020-11-20. Estimated completion is 2023-08-31.
What interventions are being tested in trial NCT04587024?
The interventions under investigation include: standard of care (OTHER), mHealth intervention (OTHER).
Who is sponsoring clinical trial NCT04587024?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04587024's enrollment target sits among peer trials
75 1069th of 2000 higher than 919 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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