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NCT04582617 · ClinicalTrials.gov registry record · NA
Investigating the Effects of Cocoa Flavanol on Cognition Assessed Online
A NA study, sponsored by Columbia University.
- Completed
- Registry status
- NA
- Development phase
- 3,959
- Enrollment target
NCT04582617: Completed NA study, sponsored by Columbia University.
NCT04582617 is a NA study that has completed, run by Columbia University. The registered enrollment target is 3,959 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (182% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04582617, a NA study, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- NA
- Development phase
- 3,959 participants
- Enrollment target
Study Summary
The COcoa Supplement and Multivitamin Outcomes Study (COSMOS; NCT02422745) is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg (-)-epicatechin), and/or a standard multivitamin supplement to reduce the risk of cardiovascular disease and cancer among men aged 60 years and older and women aged 65 years and older. This ancillary study (COSMOS Web) is being conducted among a subset of participants in COSMOS and will examine whether the cocoa extract supplements affects cognitive function in older adults.
Primary Outcome
A measure of verbal memory. The change in the number of words recalled immediately on the ModRey task (Hale et al., 2019), after one year of cocoa extract/placebo intervention.
Interventions
- DIETARY_SUPPLEMENT Multivitamin
- DIETARY_SUPPLEMENT Multivitamin placebo
- DIETARY_SUPPLEMENT Cocoa Extract
- DIETARY_SUPPLEMENT Cocoa Extract Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,959 participants |
| Start Date | 2016-08-26 |
| Est. Completion | 2020-12-31 |
| Phase | NA |
What the finished NCT04582617 record still lists
NCT04582617 is an interventional study that assigns participants to a tested intervention. Its 3,959 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (182% higher).
The record links to 0 conditions, and to 4 interventions - of which Multivitamin is the first listed.
NCT04582617 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04582617 about?
NCT04582617 is a clinical study titled "Investigating the Effects of Cocoa Flavanol on Cognition Assessed Online". The COcoa Supplement and Multivitamin Outcomes Study (COSMOS; NCT02422745) is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg (-)-epicatechin), and/or a standard multivitamin supplement to reduce the risk of cardiovascular disease an...
What is the current status of trial NCT04582617?
This trial is currently completed. It is a NA study. The enrollment target is 3,959 participants. The study started on 2016-08-26. Estimated completion is 2020-12-31.
What interventions are being tested in trial NCT04582617?
The interventions under investigation include: Multivitamin (DIETARY_SUPPLEMENT), Multivitamin placebo (DIETARY_SUPPLEMENT), Cocoa Extract (DIETARY_SUPPLEMENT), Cocoa Extract Placebo (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04582617?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04582617's enrollment target sits among peer trials
3,959 36th of 2000 higher than 1,965 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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