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NCT04563494 · ClinicalTrials.gov registry record · Phase 4

The Effects of IV vs Oral Dexamethasone on Postoperative Nausea, Vomiting, and Pain

A Phase 4 study, sponsored by University of Colorado, Denver.

Completed
Registry status
Phase 4
Development phase
127
Enrollment target

NCT04563494 is a Phase 4 study that has completed, run by University of Colorado, Denver. The registered enrollment target is 127 participants.

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The verdict

NCT04563494, a Phase 4 study, has completed, sponsored by University of Colorado, Denver.

COMPLETED
Registry status
Phase 4
Development phase
127 participants
Enrollment target

Study Summary

The hypothesis being tested in this study is that perioperative oral administration of dexamethasone, when compared to intravenous (IV) administration, offers a similar reduction in postoperative nausea and vomiting (PONV), and reduction in postoperative pain in pediatric patients undergoing tonsillectomy with or without adenoidectomy and/or tympanostomy tube placement. The specific aim of this study is to demonstrate non-inferiority of oral dexamethasone when compared to IV dexamethasone, given that there is currently a severe, sudden, and world-wide shortage of IV dexamethasone given its recent use in treating patients with covid19 disease.

Interventions

  • DRUG dexamethasone

Trial Details

FieldValue
Enrollment Target 127 participants
Start Date 2020-10-23
Est. Completion 2023-05-24
Phase Phase 4

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT04563494

The ClinicalTrials.gov registry entry for NCT04563494 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 127 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which dexamethasone is the first listed.

NCT04563494 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04563494 about?

NCT04563494 is a clinical study titled "The Effects of IV vs Oral Dexamethasone on Postoperative Nausea, Vomiting, and Pain". The hypothesis being tested in this study is that perioperative oral administration of dexamethasone, when compared to intravenous (IV) administration, offers a similar reduction in postoperative nausea and vomiting (PONV), and reduction in postoperative pain in pediatric patients undergoing tonsill...

What is the current status of trial NCT04563494?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 127 participants. The study started on 2020-10-23. Estimated completion is 2023-05-24.

What interventions are being tested in trial NCT04563494?

The interventions under investigation include: dexamethasone (DRUG).

Who is sponsoring clinical trial NCT04563494?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.