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NCT04563078 · ClinicalTrials.gov registry record · NA
Effect of TMS on PTSD Biomarkers
A NA study, sponsored by Emory University.
- Completed
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT04563078: Completed NA study, sponsored by Emory University.
NCT04563078 is a NA study that has completed, run by Emory University. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04563078, a NA study, has completed, sponsored by Emory University.
- COMPLETED
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
The study will (1) assess feasibility of a TMS treatment in an underserved population; (2) determine if this TMS treatment protocol improves PTSD symptoms and biological markers of PTSD such as brain functioning and startle responses; (3) define new brain targets for future TMS studies; (4) provide the first data for individual differences, which will help personalize treatment for PTSD patients; (5) improve knowledge of the neurobiology of PTSD and treatment response.
Primary Outcome
Amygdala reactivity during fear processing were assessed by fMRI responses as participants viewed 15 blocks each of fearful face and neutral face stimuli, while amygdala reactivity was measured. The amygdala was separated in the right and left hemispheres. fMRI measures the blood oxygen level-dependent response, a measure of how much more oxygenated blood there is in a certain brain region, which reflects activation of the brain region. A regression model was used to determine the beta value a
Interventions
- DEVICE Transcranial Magnetic Stimulation (TMS)
- PROCEDURE Sham Transcranial Magnetic Stimulation (TMS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2021-02-15 |
| Est. Completion | 2025-09-28 |
| Phase | NA |
What the finished NCT04563078 record still lists
NCT04563078 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Transcranial Magnetic Stimulation (TMS) is the first listed.
NCT04563078 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04563078 about?
NCT04563078 is a clinical study titled "Effect of TMS on PTSD Biomarkers". The study will (1) assess feasibility of a TMS treatment in an underserved population; (2) determine if this TMS treatment protocol improves PTSD symptoms and biological markers of PTSD such as brain functioning and startle responses; (3) define new brain targets for future TMS studies; (4) provide ...
What is the current status of trial NCT04563078?
This trial is currently completed. It is a NA study. The enrollment target is 50 participants. The study started on 2021-02-15. Estimated completion is 2025-09-28.
What interventions are being tested in trial NCT04563078?
The interventions under investigation include: Transcranial Magnetic Stimulation (TMS) (DEVICE), Sham Transcranial Magnetic Stimulation (TMS) (PROCEDURE).
Who is sponsoring clinical trial NCT04563078?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04563078's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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