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COMPLETED Phase 1

Dendritic Cell Vaccination With Standard Postoperative Chemoradiation for the Treatment of Adult Glioblastoma

NCT04552886 · View on ClinicalTrials.gov ↗

Study Summary

Effective treatments are desperately needed for glioblastoma (GBM) patients. This phase I clinical trial assesses the safety of a novel personalized dendritic-cell vaccine administered to GBM patients shortly after completing standard-of-care treatments. Secondary outcomes will evaluate patient progression-free survival and overall survival.

Conditions Studied

Interventions

  • BIOLOGICAL TH-1 Dendritic Cell Immunotherapy

Study Locations (2)

New Jersey

  • Cooper University Hospital — Camden

Texas

  • Memorial Hermann- Texas Medical Center — Houston

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2021-10-11
Est. Completion 2023-12-01
Phase Phase 1

Sponsor

The Cooper Health System

46 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04552886

The ClinicalTrials.gov registry entry for NCT04552886 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The Cooper Health System, which has 46 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Glioblastoma appearing as the primary indexed condition, and to 1 intervention — of which TH-1 Dendritic Cell Immunotherapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04552886 reports 2 study locations spanning 2 distinct geographic areas — top geographies include New Jersey, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04552886 about?

NCT04552886 is a clinical study titled "Dendritic Cell Vaccination With Standard Postoperative Chemoradiation for the Treatment of Adult Glioblastoma". Effective treatments are desperately needed for glioblastoma (GBM) patients. This phase I clinical trial assesses the safety of a novel personalized dendritic-cell vaccine administered to GBM patients shortly after completing standard-of-care treatments. Secondary outcomes will evaluate patient prog...

What is the current status of trial NCT04552886?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2021-10-11. Estimated completion is 2023-12-01.

What conditions does trial NCT04552886 study?

This clinical trial studies the following conditions: Glioblastoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04552886?

The interventions under investigation include: TH-1 Dendritic Cell Immunotherapy (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04552886?

This trial is sponsored by The Cooper Health System, which has 46 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04552886 being conducted?

This trial has 2 study locations across New Jersey, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial