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NCT04537377 · ClinicalTrials.gov registry record · Phase 1

A Phase I/II Study of VTX-801 in Adult Patients With Wilson's Disease

A Phase 1 study of Wilson's Disease, sponsored by Vivet Therapeutics SAS.

Active
Registry status
Phase 1
Development phase
4
Enrollment target
10
Study locations

NCT04537377 is a Phase 1 study of Wilson's Disease that is active but no longer recruiting, run by Vivet Therapeutics SAS. The registered enrollment target is 4 participants. The trial reports 10 study locations across 8 states.

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The verdict

NCT04537377, a Phase 1 study of Wilson's Disease, is active but no longer recruiting, sponsored by Vivet Therapeutics SAS.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
4 participants
Enrollment target
10
Study locations

Study Summary

The objectives of this clinical trial are to assess, for up to 5 years, the safety, tolerability and pharmacological activity of a single ascending doses of VTX-801, a gene therapy, administered intravenously (IV) to adult patients with Wilson's Disease prior to and following background WD therapy withdrawal.

Conditions Studied

Interventions

  • GENETIC VTX-801

Study Locations (10)

Other

  • Aarhus University Hospital - Aarhus
  • University Hospital Essen - Essen
  • Universitätsklinikum Tübingen (UKT) - Tübingen

California

  • UC Davis Medical Center - Sacramento

Connecticut

  • Yale University School of Medecine - New Haven

Florida

  • Advent Health - Orlando

Michigan

  • University of Michigan Health System - Ann Arbor

North Carolina

  • Wake Forest School of Medicine - Winston-Salem

Texas

  • University of Texas Southwestern Medical Center - Dallas

Surrey

  • Royal Surrey County Hospital - Guildford

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2021-09-03
Est. Completion 2029-06-18
Phase Phase 1

Sponsor

Vivet Therapeutics SAS

1 total trials

What the Registry Record Tells You About NCT04537377

The ClinicalTrials.gov registry entry for NCT04537377 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vivet Therapeutics SAS, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Wilson's Disease appearing as the primary indexed condition, and to 1 intervention - of which VTX-801 is the first listed.

NCT04537377 reports 10 study locations spanning 8 distinct geographic areas - top geographies include Other, California, Connecticut.

Frequently Asked Questions

What is clinical trial NCT04537377 about?

NCT04537377 is a clinical study titled "A Phase I/II Study of VTX-801 in Adult Patients With Wilson's Disease". The objectives of this clinical trial are to assess, for up to 5 years, the safety, tolerability and pharmacological activity of a single ascending doses of VTX-801, a gene therapy, administered intravenously (IV) to adult patients with Wilson's Disease prior to and following background WD therapy w...

What is the current status of trial NCT04537377?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2021-09-03. Estimated completion is 2029-06-18.

What conditions does trial NCT04537377 study?

This clinical trial studies the following conditions: Wilson's Disease.

What interventions are being tested in trial NCT04537377?

The interventions under investigation include: VTX-801 (GENETIC).

Who is sponsoring clinical trial NCT04537377?

This trial is sponsored by Vivet Therapeutics SAS, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04537377 being conducted?

This trial has 10 study locations across California, Connecticut, Florida, Michigan, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.