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NCT04526288 · ClinicalTrials.gov registry record · Phase 2

CPX-351 Versus Immediate Stem Cell Transplantation for the Treatment of High-Grade Myeloid Cancers With Measurable Residual Disease

A Phase 2 study, sponsored by Fred Hutchinson Cancer Center.

Terminated
Registry status
Phase 2
Development phase
1
Enrollment target

NCT04526288 is a Phase 2 study that was terminated before completion, run by Fred Hutchinson Cancer Center. The registered enrollment target is 1 participants.

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The verdict

NCT04526288, a Phase 2 study, was terminated before completion, sponsored by Fred Hutchinson Cancer Center.

TERMINATED
Registry status
Phase 2
Development phase
1 participants
Enrollment target

Study Summary

This phase II trial studies the effect of CPX-351 followed by donor stem cell transplantation versus immediate donor stem cell transplantation in treating patients with high-grade myeloid cancers with measurable residual disease. Chemotherapy drugs, such as CPX-351, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving chemotherapy before donor stem cell transplantation may help kill cancer cells in the body and make room in the patient's bone marrow for new blood-forming cells (stem cells) to grow.

Interventions

  • DRUG Liposome-encapsulated Daunorubicin-Cytarabine
  • PROCEDURE Allogeneic Hematopoietic Stem Cell Transplantation

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2021-08-09
Est. Completion 2023-08-27
Phase Phase 2

Sponsor

Fred Hutchinson Cancer Center

483 total trials

What the Registry Record Tells You About NCT04526288

The ClinicalTrials.gov registry entry for NCT04526288 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Fred Hutchinson Cancer Center, which has 483 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Liposome-encapsulated Daunorubicin-Cytarabine is the first listed.

NCT04526288 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04526288 about?

NCT04526288 is a clinical study titled "CPX-351 Versus Immediate Stem Cell Transplantation for the Treatment of High-Grade Myeloid Cancers With Measurable Residual Disease". This phase II trial studies the effect of CPX-351 followed by donor stem cell transplantation versus immediate donor stem cell transplantation in treating patients with high-grade myeloid cancers with measurable residual disease. Chemotherapy drugs, such as CPX-351, work in different ways to stop th...

What is the current status of trial NCT04526288?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 1 participants. The study started on 2021-08-09. Estimated completion is 2023-08-27.

What interventions are being tested in trial NCT04526288?

The interventions under investigation include: Liposome-encapsulated Daunorubicin-Cytarabine (DRUG), Allogeneic Hematopoietic Stem Cell Transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT04526288?

This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.