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NCT04514757 · ClinicalTrials.gov registry record · NA
Transcutaneous (Tragus) Vagal Nerve Stimulation for Post-op Afib
A NA study, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- NA
- Development phase
- 77
- Enrollment target
NCT04514757 is a NA study that has completed, run by University of California, Los Angeles. The registered enrollment target is 77 participants.
The verdict
NCT04514757, a NA study, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- NA
- Development phase
- 77 participants
- Enrollment target
Study Summary
Patients undergoing cardiac surgery are at high risk of developing atrial fibrillation (AF), with estimated rates of 30-50% and occurs at approximately 2-4 days after surgery. The autonomic nervous system is known to play a key role in AF. Animal studies have indicated that duration and inducibility of AF can be decreased with intermittent vagus nerve stimulation (VNS). In humans, literature suggests that transcutaneous (tragus) VNS (tVNS) can serve as a potentially non-invasive therapy for treatment of post-operative AF (POAF) by reducing inflammation and increasing atrial refractory period. The purpose of this study is to determine the value of tVNS in reducing the burden of POAF and days of hospitalization after cardiac surgery.
Interventions
- DEVICE active tVNS
- DEVICE sham tVNS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 77 participants |
| Start Date | 2021-09-20 |
| Est. Completion | 2024-04-25 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04514757
The ClinicalTrials.gov registry entry for NCT04514757 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 77 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which active tVNS is the first listed.
NCT04514757 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04514757 about?
NCT04514757 is a clinical study titled "Transcutaneous (Tragus) Vagal Nerve Stimulation for Post-op Afib". Patients undergoing cardiac surgery are at high risk of developing atrial fibrillation (AF), with estimated rates of 30-50% and occurs at approximately 2-4 days after surgery. The autonomic nervous system is known to play a key role in AF. Animal studies have indicated that duration and inducibility...
What is the current status of trial NCT04514757?
This trial is currently completed. It is a NA study. The enrollment target is 77 participants. The study started on 2021-09-20. Estimated completion is 2024-04-25.
What interventions are being tested in trial NCT04514757?
The interventions under investigation include: active tVNS (DEVICE), sham tVNS (DEVICE).
Who is sponsoring clinical trial NCT04514757?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
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