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NCT04509674 · ClinicalTrials.gov registry record · Phase 3

EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)

A Phase 3 study, sponsored by Boehringer Ingelheim.

Completed
Registry status
Phase 3
Development phase
6,522
Enrollment target

NCT04509674 is a Phase 3 study that has completed, run by Boehringer Ingelheim. The registered enrollment target is 6,522 participants.

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The verdict

NCT04509674, a Phase 3 study, has completed, sponsored by Boehringer Ingelheim.

COMPLETED
Registry status
Phase 3
Development phase
6,522 participants
Enrollment target

Study Summary

This is a study in adults who had a heart attack (myocardial infarction). The purpose of this study is to find out whether a medicine called empagliflozin helps to lower the chances of having to go to the hospital for heart failure and whether it lowers the chances of dying from cardiovascular disease. People who are in hospital may join the study soon after being treated for their heart attack. Participants are put into 2 groups by chance. One group takes 1 empagliflozin tablet a day. The other group takes 1 placebo tablet a day. Placebo tablets look like empagliflozin tablets but do not contain any medicine. All participants continue their standard treatment. Empagliflozin belongs to a class of medicines known as SGLT-2 inhibitors. Empagliflozin is a medicine that helps people with type 2 diabetes to lower their blood sugar. Researchers think that empagliflozin might also help people after heart attack who are at risk for heart failure, whether or not they have diabetes. Participants are in the study for about 1 to 2 years. During this time, there are about 4 visits inperson, 2 visits are done either by phone or by use of an mobile application. Results between the empagliflozin and placebo groups are compared. The doctors also regularly check the general health of the participants.

Interventions

  • DRUG Placebo
  • DRUG Empagliflozin

Trial Details

FieldValue
Enrollment Target 6,522 participants
Start Date 2020-12-16
Est. Completion 2023-11-05
Phase Phase 3

Sponsor

Boehringer Ingelheim

515 total trials

What the Registry Record Tells You About NCT04509674

The ClinicalTrials.gov registry entry for NCT04509674 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 6,522 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boehringer Ingelheim, which has 515 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04509674 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04509674 about?

NCT04509674 is a clinical study titled "EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)". This is a study in adults who had a heart attack (myocardial infarction). The purpose of this study is to find out whether a medicine called empagliflozin helps to lower the chances of having to go to the hospital for heart failure and whether it lowers the chances of dying from cardiovascular disea...

What is the current status of trial NCT04509674?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 6,522 participants. The study started on 2020-12-16. Estimated completion is 2023-11-05.

What interventions are being tested in trial NCT04509674?

The interventions under investigation include: Placebo (DRUG), Empagliflozin (DRUG).

Who is sponsoring clinical trial NCT04509674?

This trial is sponsored by Boehringer Ingelheim, which has 515 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.