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NCT04507425 · ClinicalTrials.gov registry record · NA
High Flow Nasal Cannula With Noninvasive Ventilation
A NA study, sponsored by University of Oklahoma.
- Completed
- Registry status
- NA
- Development phase
- 6
- Enrollment target
NCT04507425: Completed NA study, sponsored by University of Oklahoma.
NCT04507425 is a NA study that has completed, run by University of Oklahoma. The registered enrollment target is 6 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04507425, a NA study, has completed, sponsored by University of Oklahoma.
- COMPLETED
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
Study Summary
This is a prospective, randomized, unblinded trial of trauma patients in the ICU who are identified as being at a high risk to develop acute respiratory failure. We hope that this study will help the study team to identify how best to use a more aggressive respiratory treatment strategy in a high risk trauma population (thoracic trauma or trauma patients requiring thoracic surgery, spine surgery, or open abdominal procedures) to try and decrease the need for intubation with mechanical ventilation.
Primary Outcome
Among injured patients admitted to the intensive care unit (ICU) without being intubated, do failure rates within the first 48 hours of ICU admission differ with respect to type of initial respiratory intervention: nasal cannula, high-flow nasal cannula (HFNC), or HFNC plus non-invasive ventilation (BiPAP). Failure is defined as escalation to intubation.
Interventions
- OTHER Standard of Care - Nasal Cannula
- OTHER High-flow nasal cannula
- OTHER HFNC plus non-invasive ventilation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2020-09-01 |
| Est. Completion | 2023-07-10 |
| Phase | NA |
What the finished NCT04507425 record still lists
NCT04507425 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 3 interventions - of which Standard of Care - Nasal Cannula is the first listed.
NCT04507425 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04507425 about?
NCT04507425 is a clinical study titled "High Flow Nasal Cannula With Noninvasive Ventilation". This is a prospective, randomized, unblinded trial of trauma patients in the ICU who are identified as being at a high risk to develop acute respiratory failure. We hope that this study will help the study team to identify how best to use a more aggressive respiratory treatment strategy in a high r...
What is the current status of trial NCT04507425?
This trial is currently completed. It is a NA study. The enrollment target is 6 participants. The study started on 2020-09-01. Estimated completion is 2023-07-10.
What interventions are being tested in trial NCT04507425?
The interventions under investigation include: Standard of Care - Nasal Cannula (OTHER), High-flow nasal cannula (OTHER), HFNC plus non-invasive ventilation (OTHER).
Who is sponsoring clinical trial NCT04507425?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04507425's enrollment target sits among peer trials
6 1983rd of 2000 higher than 13 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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