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NCT04498364 · ClinicalTrials.gov registry record · NA
Extinction Learning in Adults With Tourette Syndrome
A NA study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT04498364: Completed NA study, sponsored by Johns Hopkins University.
NCT04498364 is a NA study that has completed, run by Johns Hopkins University. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04498364, a NA study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still understudied for individuals with Tourette syndrome (TS). This study examines extinction learning and extinction recall in adults with TS using an experimental task. This study will also explore the relationship between extinction processes (i.e., extinction learning and extinction recall) and treatment outcomes with behavior therapy. Findings from this investigation will be used to update the behavioral treatment model, which serves as the basis for evidence-based behavioral interventions.
Primary Outcome
Patient will nominate up to five motor and five vocal tics they deem bothersome on the HM/VTS. Each bothersome tic is then rated by a clinician on the composite two (vocal and motor) 5-point HM/VTS scale ranging from none (0) to severe (4) for the motor as well as vocal tics. The individual tic scores are summed (minimum of 0 and maximum of 40) and averaged together to create an average tic severity score.
Interventions
- BEHAVIORAL Habit Reversal Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2020-09-18 |
| Est. Completion | 2023-10-17 |
| Phase | NA |
What the finished NCT04498364 record still lists
NCT04498364 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Habit Reversal Training is the first listed.
NCT04498364 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04498364 about?
NCT04498364 is a clinical study titled "Extinction Learning in Adults With Tourette Syndrome". Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still understudied for individuals with Tourette syndrome (TS). This study examin...
What is the current status of trial NCT04498364?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2020-09-18. Estimated completion is 2023-10-17.
What interventions are being tested in trial NCT04498364?
The interventions under investigation include: Habit Reversal Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT04498364?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04498364's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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