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NCT04495894 · ClinicalTrials.gov registry record · Phase 2

Pre-Incisional Ketorolac for Patients Undergoing Surgery for Non-Small Cell Lung Cancer and Renal Cell Carcinoma

A Phase 2 study, sponsored by Emory University.

Terminated
Registry status
Phase 2
Development phase
68
Enrollment target

NCT04495894 is a Phase 2 study that was terminated before completion, run by Emory University. The registered enrollment target is 68 participants.

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The verdict

NCT04495894, a Phase 2 study, was terminated before completion, sponsored by Emory University.

TERMINATED
Registry status
Phase 2
Development phase
68 participants
Enrollment target

Study Summary

This is a pilot study of biomarker evaluation and safety of pre-incisional ketorolac for patients undergoing surgical resection for non-small cell lung cancer and renal cell carcinoma. There is significant promise in the use of preoperative ketorolac to decrease the inflammatory response after surgical resection of tumors, thereby potentially reducing the risk of distant metastatic tumor spread and improving survival. This research will advance scientific knowledge by studying the safety of a preoperative dose of ketorolac prior to major surgical resection, which needs to be assessed prior to proceeding with a larger phase II study designed to evaluate traditional efficacy endpoints such as recurrence and overall survival.

Interventions

  • DRUG Preoperative Ketorolac

Trial Details

FieldValue
Enrollment Target 68 participants
Start Date 2020-08-24
Est. Completion 2024-02-01
Phase Phase 2

Sponsor

Emory University

1,208 total trials

What the Registry Record Tells You About NCT04495894

The ClinicalTrials.gov registry entry for NCT04495894 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 68 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Emory University, which has 1,208 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Preoperative Ketorolac is the first listed.

NCT04495894 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04495894 about?

NCT04495894 is a clinical study titled "Pre-Incisional Ketorolac for Patients Undergoing Surgery for Non-Small Cell Lung Cancer and Renal Cell Carcinoma". This is a pilot study of biomarker evaluation and safety of pre-incisional ketorolac for patients undergoing surgical resection for non-small cell lung cancer and renal cell carcinoma. There is significant promise in the use of preoperative ketorolac to decrease the inflammatory response after surgi...

What is the current status of trial NCT04495894?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 68 participants. The study started on 2020-08-24. Estimated completion is 2024-02-01.

What interventions are being tested in trial NCT04495894?

The interventions under investigation include: Preoperative Ketorolac (DRUG).

Who is sponsoring clinical trial NCT04495894?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.