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NCT04485039 · ClinicalTrials.gov registry record · Phase 4
Drug-drug Interaction Study of TPOXX When Co-administered With Phosphate Binders
A Phase 4 study, sponsored by SIGA Technologies.
- Completed
- Registry status
- Phase 4
- Development phase
- 44
- Enrollment target
NCT04485039: Completed Phase 4 study, sponsored by SIGA Technologies.
NCT04485039 is a Phase 4 study that has completed, run by SIGA Technologies. The registered enrollment target is 44 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04485039, a Phase 4 study, has completed, sponsored by SIGA Technologies.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 44 participants
- Enrollment target
Study Summary
An open-label, drug-drug interaction study with TPOXX and phosphate binders.
Primary Outcome
Area under the plasma concentration of vs. time curve (AUC) of TPOXX from 0 extrapolated to infinity
Interventions
- DRUG Tecovirimat
- DRUG sevelamer carbonate oral tablet
- DRUG sucroferric oxyhydroxide chewable tablet
- DRUG calcium acetate oral tablet
- DRUG Lanthanum Carbonate Chewable Tablet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2022-06-08 |
| Est. Completion | 2023-04-23 |
| Phase | Phase 4 |
What the finished NCT04485039 record still lists
NCT04485039 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 5 interventions - of which Tecovirimat is the first listed.
NCT04485039 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04485039 about?
NCT04485039 is a clinical study titled "Drug-drug Interaction Study of TPOXX When Co-administered With Phosphate Binders". An open-label, drug-drug interaction study with TPOXX and phosphate binders.
What is the current status of trial NCT04485039?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 44 participants. The study started on 2022-06-08. Estimated completion is 2023-04-23.
What interventions are being tested in trial NCT04485039?
The interventions under investigation include: Tecovirimat (DRUG), sevelamer carbonate oral tablet (DRUG), sucroferric oxyhydroxide chewable tablet (DRUG), calcium acetate oral tablet (DRUG), Lanthanum Carbonate Chewable Tablet (DRUG).
Who is sponsoring clinical trial NCT04485039?
This trial is sponsored by SIGA Technologies, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04485039's enrollment target sits among peer trials
44 1363rd of 2000 higher than 630 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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