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NCT04483206 · ClinicalTrials.gov registry record · Phase 1
Personalized Autologous Transplant for Multiple Myeloma
A Phase 1 study of Multiple Myeloma, sponsored by Emory University.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 90
- Enrollment target
- 2
- Study locations
NCT04483206 is a Phase 1 study of Multiple Myeloma that is actively recruiting participants, run by Emory University. The registered enrollment target is 90 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (84% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT04483206, a Phase 1 study of Multiple Myeloma, is actively recruiting participants, sponsored by Emory University.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 90 participants
- Enrollment target
- 2
- Study locations
Study Summary
This phase I trial studies the best dose and side effects of mephalan in treating patients with multiple myeloma who are undergoing stem cell transplant. Chemotherapy drugs, such as mephalan, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial uses a new method of dosing that is based on analysis of each individual's blood levels of melphalan after receiving a part of the dose, termed pharmacokinetic analysis. This may help to learn more about how to dose melphalan correctly and which patients are likely to benefit from a personalized dose.
Conditions Studied
Interventions
- DRUG Melphalan
- OTHER Questionnaire Administration
- PROCEDURE Autologous Hematopoietic Stem Cell Transplantation
Study Locations (2)
Georgia
- Winship Cancer Institute of Emory University - Atlanta
Illinois
- University Illinois Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2021-05-20 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04483206
The ClinicalTrials.gov registry entry for NCT04483206 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (84% lower). The listed sponsor is Emory University, which has 1,208 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 3 interventions - of which Melphalan is the first listed.
NCT04483206 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Georgia, Illinois.
Frequently Asked Questions
What is clinical trial NCT04483206 about?
NCT04483206 is a clinical study titled "Personalized Autologous Transplant for Multiple Myeloma". This phase I trial studies the best dose and side effects of mephalan in treating patients with multiple myeloma who are undergoing stem cell transplant. Chemotherapy drugs, such as mephalan, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them fro...
What is the current status of trial NCT04483206?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 90 participants. The study started on 2021-05-20. Estimated completion is 2026-12-31.
What conditions does trial NCT04483206 study?
This clinical trial studies the following conditions: Multiple Myeloma.
What interventions are being tested in trial NCT04483206?
The interventions under investigation include: Melphalan (DRUG), Questionnaire Administration (OTHER), Autologous Hematopoietic Stem Cell Transplantation (PROCEDURE).
Who is sponsoring clinical trial NCT04483206?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04483206 being conducted?
This trial has 2 study locations across Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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