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NCT04478227 · ClinicalTrials.gov registry record · Early Phase 1
TPO-Mimetic Use in Children for Hematopoietic Failure
A Early Phase 1 study of Aplastic Anemia and Thrombocytopenia, sponsored by Anjali Sharathkumar.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT04478227: Completed Early Phase 1 study of Aplastic Anemia and Thrombocytopenia, sponsored by Anjali Sharathkumar.
NCT04478227 is a Early Phase 1 study of Aplastic Anemia and Thrombocytopenia that has completed, run by Anjali Sharathkumar. The registered enrollment target is 15 participants, below the 42-participant average among 23 other Aplastic Anemia trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04478227, a Early Phase 1 study of Aplastic Anemia and Thrombocytopenia, has completed, sponsored by Anjali Sharathkumar.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
This is an open label, prospective Pilot interventional study will investigate the safety and efficacy of Romiplostim, thrombopoietin (TPO) mimetic, in children (ages: 0 to 21 years) with broad scope of bone marrow failure disorders including acquired and inherited conditions as a first line of therapy along with standard of care.
Primary Outcome
Categorize and quantify AEs per CTCAE version 5.0
Conditions Studied
Interventions
- DRUG Romiplostim
Study Locations (1)
Iowa
- University of Iowa Hospitals & Clinics - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2020-08-18 |
| Est. Completion | 2024-01-18 |
| Phase | Early Phase 1 |
What the finished NCT04478227 record still lists
NCT04478227 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 42-participant average among 23 other Aplastic Anemia trials with a reported enrollment target (64% lower).
The record links to 5 conditions, with Aplastic Anemia appearing as the primary indexed condition, and to 1 intervention - of which Romiplostim is the first listed.
NCT04478227 reports a single indexed study location in Iowa.
Frequently Asked Questions
What is clinical trial NCT04478227 about?
NCT04478227 is a clinical study titled "TPO-Mimetic Use in Children for Hematopoietic Failure". This is an open label, prospective Pilot interventional study will investigate the safety and efficacy of Romiplostim, thrombopoietin (TPO) mimetic, in children (ages: 0 to 21 years) with broad scope of bone marrow failure disorders including acquired and inherited conditions as a first line of ther...
What is the current status of trial NCT04478227?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 15 participants. The study started on 2020-08-18. Estimated completion is 2024-01-18.
What conditions does trial NCT04478227 study?
This clinical trial studies the following conditions: Aplastic Anemia, Thrombocytopenia, Myelodysplastic Syndrome (MDS), Bone Marrow Failure Disorders, Refractory Cytopenia of Childhood.
What interventions are being tested in trial NCT04478227?
The interventions under investigation include: Romiplostim (DRUG).
Who is sponsoring clinical trial NCT04478227?
This trial is sponsored by Anjali Sharathkumar, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04478227 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04478227's enrollment target sits among peer trials
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participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aplastic Anemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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