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NCT04475523 · ClinicalTrials.gov registry record · Phase 1

Phase 1 Study of CI-8993 Anti-VISTA Antibody in Patients With Advanced Solid Tumor Malignancies

A Phase 1 study, sponsored by Curis.

Completed
Registry status
Phase 1
Development phase
26
Enrollment target

NCT04475523 is a Phase 1 study that has completed, run by Curis. The registered enrollment target is 26 participants.

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The verdict

NCT04475523, a Phase 1 study, has completed, sponsored by Curis.

COMPLETED
Registry status
Phase 1
Development phase
26 participants
Enrollment target

Study Summary

This is a phase 1, open-label, multicenter dose-escalation study to determine the RP2D of CI 8993 for administration to patients with relapsed/refractory solid tumors by evaluating the safety and tolerability and characterizing the PK, PD, and anti cancer activity of CI-8993 in this population.

Interventions

  • DRUG CI-8993

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2020-09-22
Est. Completion 2023-05-19
Phase Phase 1

Sponsor

Curis

12 total trials

What the Registry Record Tells You About NCT04475523

The ClinicalTrials.gov registry entry for NCT04475523 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Curis, which has 12 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which CI-8993 is the first listed.

NCT04475523 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04475523 about?

NCT04475523 is a clinical study titled "Phase 1 Study of CI-8993 Anti-VISTA Antibody in Patients With Advanced Solid Tumor Malignancies". This is a phase 1, open-label, multicenter dose-escalation study to determine the RP2D of CI 8993 for administration to patients with relapsed/refractory solid tumors by evaluating the safety and tolerability and characterizing the PK, PD, and anti cancer activity of CI-8993 in this population.

What is the current status of trial NCT04475523?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2020-09-22. Estimated completion is 2023-05-19.

What interventions are being tested in trial NCT04475523?

The interventions under investigation include: CI-8993 (DRUG).

Who is sponsoring clinical trial NCT04475523?

This trial is sponsored by Curis, which has 12 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.