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NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
NCT04471909 · View on ClinicalTrials.gov ↗
Study Summary
Prospective, non-randomized, multi-center clinical investigation of the NEXUS™ Aortic Arch Stent Graft System (NEXUSTM) for the treatment of thoracic aortic lesions involving the aortic arch with a proximal landing zone, native or previously implanted surgical graft, in the ascending aorta and with a brachiocephalic trunk native landing zone.
Conditions Studied
Interventions
- DEVICE NEXUS Aortic Stent Graft System
Study Locations (20)
California
- University of California San Diego Medical Center — La Jolla
- UC Davis Health — Sacramento
- Stanford University School of Medicine — Stanford
North Carolina
- University of North Carolina — Chapel Hill
- Atrium Health — Charlotte
- Duke University Medical Center — Durham
New York
- The Mount Sinai Medical Center — New York
- Northwell Health Lenox Hill Hospital — New York
Alabama
- University of Alabama Birmingham — Birmingham
Colorado
- University of Colorado — Aurora
Connecticut
- Hartford Hospital — Hartford
District of Columbia
- MedStar Washington Hospital — Washington D.C.
Florida
- Advent Health Orlando — Orlando
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2020-10-20 |
| Est. Completion | 2029-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04471909
The ClinicalTrials.gov registry entry for NCT04471909 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Endospan, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 4 conditions, with Aortic Aneurysm appearing as the primary indexed condition, and to 1 intervention — of which NEXUS Aortic Stent Graft System is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04471909 reports 20 study locations spanning 15 distinct geographic areas — top geographies include California, North Carolina, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04471909 about?
NCT04471909 is a clinical study titled "NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness". Prospective, non-randomized, multi-center clinical investigation of the NEXUS™ Aortic Arch Stent Graft System (NEXUSTM) for the treatment of thoracic aortic lesions involving the aortic arch with a proximal landing zone, native or previously implanted surgical graft, in the ascending aorta and with ...
What is the current status of trial NCT04471909?
This trial is currently recruiting. It is a NA study. The enrollment target is 110 participants. The study started on 2020-10-20. Estimated completion is 2029-10.
What conditions does trial NCT04471909 study?
This clinical trial studies the following conditions: Aortic Aneurysm, Aortic Dissection, Intramural Hematoma, Penetrating Aortic Ulcer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04471909?
The interventions under investigation include: NEXUS Aortic Stent Graft System (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04471909?
This trial is sponsored by Endospan, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04471909 being conducted?
This trial has 20 study locations across Alabama, California, Colorado, Connecticut, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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