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NCT04469556 · ClinicalTrials.gov registry record · Phase 2
Pancreatic Adenocarcinoma Signature Stratification for Treatment
A Phase 2 study, sponsored by University Health Network, Toronto.
- Completed
- Registry status
- Phase 2
- Development phase
- 150
- Enrollment target
NCT04469556: Completed Phase 2 study, sponsored by University Health Network, Toronto.
NCT04469556 is a Phase 2 study that has completed, run by University Health Network, Toronto. The registered enrollment target is 150 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (13% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04469556, a Phase 2 study, has completed, sponsored by University Health Network, Toronto.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 150 participants
- Enrollment target
Study Summary
This is a randomized multicentre phase II trial with a large translational component. The trial will evaluate the two standard chemotherapy regimens: modified folfirinox (mFFX) and gemcitabine/nab-paclitaxel (GA), in patients with untreated metastatic pancreatic ductal adenocarcinoma. Integrated into this phase II trial are a number of laboratory components including molecular profiling, patient derived organoid establishment, and drug testing sensitivity and other biomarkers.
Primary Outcome
Time from the date of randomization to progression based on the radiology assessment of response using RECIST v1.1, or death, whichever is earlier
Interventions
- DRUG Folfirinox
- DRUG Gemcitabine/nab-paclitaxel
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2020-10-14 |
| Est. Completion | 2025-03-05 |
| Phase | Phase 2 |
What the finished NCT04469556 record still lists
NCT04469556 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (13% higher).
The record links to 0 conditions, and to 2 interventions - of which Folfirinox is the first listed.
NCT04469556 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04469556 about?
NCT04469556 is a clinical study titled "Pancreatic Adenocarcinoma Signature Stratification for Treatment". This is a randomized multicentre phase II trial with a large translational component. The trial will evaluate the two standard chemotherapy regimens: modified folfirinox (mFFX) and gemcitabine/nab-paclitaxel (GA), in patients with untreated metastatic pancreatic ductal adenocarcinoma. Integrated int...
What is the current status of trial NCT04469556?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 150 participants. The study started on 2020-10-14. Estimated completion is 2025-03-05.
What interventions are being tested in trial NCT04469556?
The interventions under investigation include: Folfirinox (DRUG), Gemcitabine/nab-paclitaxel (DRUG).
Who is sponsoring clinical trial NCT04469556?
This trial is sponsored by University Health Network, Toronto, which has 23 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04469556's enrollment target sits among peer trials
150 455th of 2000 higher than 1,510 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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