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NCT04468230 · ClinicalTrials.gov registry record · Phase 2
Study of Nicotine for Pain Associated With Chemotherapy-Induced Peripheral Neuropathy
A Phase 2 study, sponsored by Virginia Commonwealth University.
- Terminated
- Registry status
- Phase 2
- Development phase
- 4
- Enrollment target
NCT04468230: Clinical Trial Phase 2 study, sponsored by Virginia Commonwealth University.
NCT04468230 is a Phase 2 study that was terminated before completion, run by Virginia Commonwealth University. The registered enrollment target is 4 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04468230, a Phase 2 study, was terminated before completion, sponsored by Virginia Commonwealth University.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 4 participants
- Enrollment target
Study Summary
Assess the efficacy of short-term nicotine transdermal patch administration for the treatment of chemotherapy-induced peripheral neuropathy (CIPN) in cancer stable patients or patients in remission.
Primary Outcome
To assess the efficacy, of the nicotine transdermal patch administration in the treatment of CIPN in patients whose cancer is stable or in remission as defined by a ≥ 2.7 point decrease in the total sensory score of the European Organization for Research and Treatment of Cancer Quality of Life-cancer induced peripheral neuropathy (CIPN20) Questionnaire (EORTC QLQ-CIPN-20) (eg, an improvement in the patients quality of life by one grade). The QLQ-CIPN20 numerical score has a range of 19-76, in wh
Interventions
- DRUG Nicotine Transdermal Patch
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2020-07-31 |
| Est. Completion | 2022-05-31 |
| Phase | Phase 2 |
Why NCT04468230 stopped before completion
NCT04468230 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Nicotine Transdermal Patch is the first listed.
NCT04468230 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04468230 about?
NCT04468230 is a clinical study titled "Study of Nicotine for Pain Associated With Chemotherapy-Induced Peripheral Neuropathy". Assess the efficacy of short-term nicotine transdermal patch administration for the treatment of chemotherapy-induced peripheral neuropathy (CIPN) in cancer stable patients or patients in remission.
What is the current status of trial NCT04468230?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2020-07-31. Estimated completion is 2022-05-31.
What interventions are being tested in trial NCT04468230?
The interventions under investigation include: Nicotine Transdermal Patch (DRUG).
Who is sponsoring clinical trial NCT04468230?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04468230's enrollment target sits among peer trials
4 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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