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NCT04463680 · ClinicalTrials.gov registry record · Phase 4

Rifampin and the Contraceptive Implant

A Phase 4 study, sponsored by University of Colorado, Denver.

Completed
Registry status
Phase 4
Development phase
24
Enrollment target

NCT04463680: Completed Phase 4 study, sponsored by University of Colorado, Denver.

NCT04463680 is a Phase 4 study that has completed, run by University of Colorado, Denver. The registered enrollment target is 24 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04463680, a Phase 4 study, has completed, sponsored by University of Colorado, Denver.

COMPLETED
Registry status
Phase 4
Development phase
24 participants
Enrollment target

Study Summary

It is important for women taking rifampin to be aware if they are at greater risk of an unintended pregnancy while on the implant. An unintended pregnancy has many social, emotional, and financial impacts on women and society. Rifampin is also a Class C medication for pregnancy and could have potential negative effects on a developing fetus. Additionally, women considering rifampin for treatment of LTBI face additional risks with an unintended pregnancy, making the reliability of contraception even more important for these women. The results of this study can directly inform counseling on a national and international basis for women who use the contraceptive implant and are considering their treatment options for LTBI.

Primary Outcome

Blood drawn before and after rifampin administration (2 weeks) for serum extraction and etonogestrel analysis

Interventions

  • DRUG Rifampin 600 MG

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2020-09-23
Est. Completion 2022-02-22
Phase Phase 4
University of Colorado, Denver

1,283 total trials

What the finished NCT04463680 record still lists

NCT04463680 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 1 intervention - of which Rifampin 600 MG is the first listed.

NCT04463680 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04463680 about?

NCT04463680 is a clinical study titled "Rifampin and the Contraceptive Implant". It is important for women taking rifampin to be aware if they are at greater risk of an unintended pregnancy while on the implant. An unintended pregnancy has many social, emotional, and financial impacts on women and society. Rifampin is also a Class C medication for pregnancy and could have potent...

What is the current status of trial NCT04463680?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 24 participants. The study started on 2020-09-23. Estimated completion is 2022-02-22.

What interventions are being tested in trial NCT04463680?

The interventions under investigation include: Rifampin 600 MG (DRUG).

Who is sponsoring clinical trial NCT04463680?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04463680's enrollment target sits among peer trials

24 1699th of 2000 higher than 276 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04463680, the US trial registry maintained by the National Library of Medicine. NCT04463680 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.