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NCT04463004 · ClinicalTrials.gov registry record · Phase 2

Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation

A Phase 2 study, sponsored by Virginia Commonwealth University.

Completed
Registry status
Phase 2
Development phase
2
Enrollment target

NCT04463004 is a Phase 2 study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 2 participants.

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The verdict

NCT04463004, a Phase 2 study, has completed, sponsored by Virginia Commonwealth University.

COMPLETED
Registry status
Phase 2
Development phase
2 participants
Enrollment target

Study Summary

The purpose of this prospective, Phase 2, multicenter, blinded, randomized placebo controlled study is to demonstrate that early treatment with mavrilimumab prevents progression of respiratory failure in patients with severe COVID-19 pneumonia and clinical and biological features of hyper-inflammation.

Interventions

  • DRUG Placebos
  • DRUG Mavrilimumab

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2020-09-02
Est. Completion 2020-11-30
Phase Phase 2

Sponsor

Virginia Commonwealth University

558 total trials

What the Registry Record Tells You About NCT04463004

The ClinicalTrials.gov registry entry for NCT04463004 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Virginia Commonwealth University, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebos is the first listed.

NCT04463004 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04463004 about?

NCT04463004 is a clinical study titled "Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation". The purpose of this prospective, Phase 2, multicenter, blinded, randomized placebo controlled study is to demonstrate that early treatment with mavrilimumab prevents progression of respiratory failure in patients with severe COVID-19 pneumonia and clinical and biological features of hyper-inflammati...

What is the current status of trial NCT04463004?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 2 participants. The study started on 2020-09-02. Estimated completion is 2020-11-30.

What interventions are being tested in trial NCT04463004?

The interventions under investigation include: Placebos (DRUG), Mavrilimumab (DRUG).

Who is sponsoring clinical trial NCT04463004?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.