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NCT04456608 · ClinicalTrials.gov registry record · Phase 4
Genetic and Dietary Predictors of Anti-platelet Response
A Phase 4 study, sponsored by University of Washington.
- Terminated
- Registry status
- Phase 4
- Development phase
- 126
- Enrollment target
NCT04456608: Clinical Trial Phase 4 study, sponsored by University of Washington.
NCT04456608 is a Phase 4 study that was terminated before completion, run by University of Washington. The registered enrollment target is 126 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (76% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04456608, a Phase 4 study, was terminated before completion, sponsored by University of Washington.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 126 participants
- Enrollment target
Study Summary
This study will investigate differences in platelet aggregation under basal and aspirin-treated conditions in American Indian and Alaska Native people who have extreme levels (low and high) of n-3 polyunsaturated fatty acids (n-3 PUFAs, EPA and DHA) in red blood cell membranes. The study will also determine whether or not platelet aggregation under the different conditions is modified by CYP4A11, CYP4F2, CYP4F11, PEAR1, and ACTN1 gene variation.
Primary Outcome
Citrated blood samples will be treated with collagen/epinephrine and collagen/ADP and the time to reach an aggregation endpoint will be measured.
Interventions
- DRUG Aspirin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 126 participants |
| Start Date | 2016-08-01 |
| Est. Completion | 2023-07-31 |
| Phase | Phase 4 |
Why NCT04456608 stopped before completion
NCT04456608 is an interventional study that assigns participants to a tested intervention. The registered 126 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (76% lower).
The record links to 0 conditions, and to 1 intervention - of which Aspirin is the first listed.
NCT04456608 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04456608 about?
NCT04456608 is a clinical study titled "Genetic and Dietary Predictors of Anti-platelet Response". This study will investigate differences in platelet aggregation under basal and aspirin-treated conditions in American Indian and Alaska Native people who have extreme levels (low and high) of n-3 polyunsaturated fatty acids (n-3 PUFAs, EPA and DHA) in red blood cell membranes. The study will also d...
What is the current status of trial NCT04456608?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 126 participants. The study started on 2016-08-01. Estimated completion is 2023-07-31.
What interventions are being tested in trial NCT04456608?
The interventions under investigation include: Aspirin (DRUG).
Who is sponsoring clinical trial NCT04456608?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04456608's enrollment target sits among peer trials
126 646th of 2000 higher than 1,354 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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