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NCT04456452 · ClinicalTrials.gov registry record · Phase 1
Study of Ampion for the Treatment of Adult COVID-19 Patients Requiring Oxygen Supplementation
A Phase 1 study, sponsored by Ampio Pharmaceuticals..
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT04456452: Completed Phase 1 study, sponsored by Ampio Pharmaceuticals..
NCT04456452 is a Phase 1 study that has completed, run by Ampio Pharmaceuticals.. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04456452, a Phase 1 study, has completed, sponsored by Ampio Pharmaceuticals..
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
This is a Phase 1 randomized study to evaluate the safety, tolerability and efficacy of IV Ampion in improving the clinical course and outcomes of patients hospitalized with COVID-19 infection who require supplemental oxygen.
Primary Outcome
Incidence and severity of adverse events
Interventions
- OTHER Standard of Care
- BIOLOGICAL Ampion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2020-07-27 |
| Est. Completion | 2020-11-30 |
| Phase | Phase 1 |
What the finished NCT04456452 record still lists
NCT04456452 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 2 interventions - of which Standard of Care is the first listed.
NCT04456452 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04456452 about?
NCT04456452 is a clinical study titled "Study of Ampion for the Treatment of Adult COVID-19 Patients Requiring Oxygen Supplementation". This is a Phase 1 randomized study to evaluate the safety, tolerability and efficacy of IV Ampion in improving the clinical course and outcomes of patients hospitalized with COVID-19 infection who require supplemental oxygen.
What is the current status of trial NCT04456452?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2020-07-27. Estimated completion is 2020-11-30.
What interventions are being tested in trial NCT04456452?
The interventions under investigation include: Standard of Care (OTHER), Ampion (BIOLOGICAL).
Who is sponsoring clinical trial NCT04456452?
This trial is sponsored by Ampio Pharmaceuticals., which has 12 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04456452's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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