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NCT04446975 · ClinicalTrials.gov registry record · NA
Best Practice Alert for Opioid Prescribing
A NA study, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- NA
- Development phase
- 21,689
- Enrollment target
NCT04446975: Completed NA study, sponsored by University of Colorado, Denver.
NCT04446975 is a NA study that has completed, run by University of Colorado, Denver. The registered enrollment target is 21,689 participants, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (1446% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04446975, a NA study, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- NA
- Development phase
- 21,689 participants
- Enrollment target
Study Summary
The investigators will embed a developed decision support tool into the electronic health record (EHR) to individualize pain therapy in surgical patients after hospital discharge and test its performance in a pragmatic clinical trial. Preliminary data indicate that current opioid prescription practice after surgery follows a "one size fits all" pattern. In-hospital opioid use prior to discharge serves as a reliable indicator to estimate needs for analgesic medications at home. The investigators will test the hypothesis that the existing tool will enable providers to write need-based prescriptions based on prior-to-discharge opioid use, empower patients to maximize alternatives to opioids (ALTO) therapies at home, while minimizing the need for rescue prescriptions. The investigators will test this tool prospectively in a cohort of \~1,000 providers (primary subjects) and \~39,000 surgical patients (secondary subjects) in four University of Colorado Health (UCHealth) hospitals (clusters to be exposed versus (vs.) non-exposed to the intervention).
Primary Outcome
Prescribed milligram morphine equivalents (MME) discharge opioid dose as recorded in the electronic health record
Interventions
- OTHER BPA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21,689 participants |
| Start Date | 2020-07-07 |
| Est. Completion | 2021-06-08 |
| Phase | NA |
What the finished NCT04446975 record still lists
NCT04446975 is an interventional study that assigns participants to a tested intervention. Its 21,689 participants enrollment target places it among the larger protocols in the corpus, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (1446% higher).
The record links to 0 conditions, and to 1 intervention - of which BPA is the first listed.
NCT04446975 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04446975 about?
NCT04446975 is a clinical study titled "Best Practice Alert for Opioid Prescribing". The investigators will embed a developed decision support tool into the electronic health record (EHR) to individualize pain therapy in surgical patients after hospital discharge and test its performance in a pragmatic clinical trial. Preliminary data indicate that current opioid prescription pract...
What is the current status of trial NCT04446975?
This trial is currently completed. It is a NA study. The enrollment target is 21,689 participants. The study started on 2020-07-07. Estimated completion is 2021-06-08.
What interventions are being tested in trial NCT04446975?
The interventions under investigation include: BPA (OTHER).
Who is sponsoring clinical trial NCT04446975?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04446975's enrollment target sits among peer trials
21,689 10th of 2000 higher than 1,991 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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