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NCT04437888 · ClinicalTrials.gov registry record · Early Phase 1
Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty
A Early Phase 1 study, sponsored by Dartmouth-Hitchcock Medical Center.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 200
- Enrollment target
NCT04437888: Completed Early Phase 1 study, sponsored by Dartmouth-Hitchcock Medical Center.
NCT04437888 is a Early Phase 1 study that has completed, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 200 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (277% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04437888, a Early Phase 1 study, has completed, sponsored by Dartmouth-Hitchcock Medical Center.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 200 participants
- Enrollment target
Study Summary
Prospective randomized double blinded, placebo controlled study that will evaluate the effect of intra-operative ketamine administration on post-operative analgesic requirements and self-reported pain in patients undergoing total hip and total knee arthroplasty who demonstrate high levels of pain catastrophizing.
Primary Outcome
Morphine consumption will be measured in a pain diary for 6- weeks post-surgical procedure. Decreased is morphine consumption will indicate effectiveness of ketamine administration
Interventions
- DRUG Ketamine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2020-09-14 |
| Est. Completion | 2024-06-01 |
| Phase | Early Phase 1 |
What the finished NCT04437888 record still lists
NCT04437888 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (277% higher).
The record links to 0 conditions, and to 1 intervention - of which Ketamine is the first listed.
NCT04437888 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04437888 about?
NCT04437888 is a clinical study titled "Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty". Prospective randomized double blinded, placebo controlled study that will evaluate the effect of intra-operative ketamine administration on post-operative analgesic requirements and self-reported pain in patients undergoing total hip and total knee arthroplasty who demonstrate high levels of pain ca...
What is the current status of trial NCT04437888?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 200 participants. The study started on 2020-09-14. Estimated completion is 2024-06-01.
What interventions are being tested in trial NCT04437888?
The interventions under investigation include: Ketamine (DRUG).
Who is sponsoring clinical trial NCT04437888?
This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04437888's enrollment target sits among peer trials
200 60th of 2000 higher than 1,934 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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