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NCT04435821 · ClinicalTrials.gov registry record · Phase 1
PET/MRI in the Diagnosis of Pediatric Chronic Pain
A Phase 1 study, sponsored by Stanford University.
- Completed
- Registry status
- Phase 1
- Development phase
- 5
- Enrollment target
NCT04435821: Completed Phase 1 study, sponsored by Stanford University.
NCT04435821 is a Phase 1 study that has completed, run by Stanford University. The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04435821, a Phase 1 study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
\[18F\]FTC-146 is a sigma-1 receptor detector and is an experimental radiotracer. Several studies have implicated involvement of sigma-1 receptors in generation and perpetuation of chronic pain conditions, while others are investigating anti sigma-1 receptor drugs for treatment of chronic pain. Using \[18F\]-FTC-146 and PET/MRI, we hope to learn what is the best approach to identify the source of pain generation and characterize the disease in pediatric patients with chronic pain.
Primary Outcome
Biodistribution of \[18F\]FTC-146 represented as Standardized Uptake Value max (SUVmax) in pain patients.
Interventions
- DRUG [18F]FTC-146
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2020-11-19 |
| Est. Completion | 2024-10-31 |
| Phase | Phase 1 |
What the finished NCT04435821 record still lists
NCT04435821 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which [18F]FTC-146 is the first listed.
NCT04435821 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04435821 about?
NCT04435821 is a clinical study titled "PET/MRI in the Diagnosis of Pediatric Chronic Pain". \[18F\]FTC-146 is a sigma-1 receptor detector and is an experimental radiotracer. Several studies have implicated involvement of sigma-1 receptors in generation and perpetuation of chronic pain conditions, while others are investigating anti sigma-1 receptor drugs for treatment of chronic pain. Usin...
What is the current status of trial NCT04435821?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2020-11-19. Estimated completion is 2024-10-31.
What interventions are being tested in trial NCT04435821?
The interventions under investigation include: [18F]FTC-146 (DRUG).
Who is sponsoring clinical trial NCT04435821?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04435821's enrollment target sits among peer trials
5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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