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NCT04432298 · ClinicalTrials.gov registry record · Phase 2

Study of the Efficacy and Safety of Intravenous Pamrevlumab, in Hospitalized Participants With Acute COVID-19 Disease

A Phase 2 study, sponsored by Kyntra Bio.

Terminated
Registry status
Phase 2
Development phase
22
Enrollment target

NCT04432298: Clinical Trial Phase 2 study, sponsored by Kyntra Bio.

NCT04432298 is a Phase 2 study that was terminated before completion, run by Kyntra Bio. The registered enrollment target is 22 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04432298, a Phase 2 study, was terminated before completion, sponsored by Kyntra Bio.

TERMINATED
Registry status
Phase 2
Development phase
22 participants
Enrollment target

Study Summary

This study evaluates the efficacy and safety of intravenous (IV) infusions of pamrevlumab when compared with placebo in participants who are hospitalized with acute COVID-19 disease.

Interventions

  • DRUG Placebo
  • DRUG Pamrevlumab

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2020-06-20
Est. Completion 2021-03-22
Phase Phase 2
Kyntra Bio

30 total trials

Why NCT04432298 stopped before completion

NCT04432298 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04432298 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04432298 about?

NCT04432298 is a clinical study titled "Study of the Efficacy and Safety of Intravenous Pamrevlumab, in Hospitalized Participants With Acute COVID-19 Disease". This study evaluates the efficacy and safety of intravenous (IV) infusions of pamrevlumab when compared with placebo in participants who are hospitalized with acute COVID-19 disease.

What is the current status of trial NCT04432298?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 22 participants. The study started on 2020-06-20. Estimated completion is 2021-03-22.

What interventions are being tested in trial NCT04432298?

The interventions under investigation include: Placebo (DRUG), Pamrevlumab (DRUG).

Who is sponsoring clinical trial NCT04432298?

This trial is sponsored by Kyntra Bio, which has 30 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04432298's enrollment target sits among peer trials

22 1790th of 2000 higher than 207 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04432298, the US trial registry maintained by the National Library of Medicine. NCT04432298 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.