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NCT04432090 · ClinicalTrials.gov registry record · Phase 2
GPR119 Agonist for Hypoglycemia in Type 1 Diabetes
A Phase 2 study, sponsored by AdventHealth Translational Research Institute.
- Completed
- Registry status
- Phase 2
- Development phase
- 110
- Enrollment target
NCT04432090: Completed Phase 2 study, sponsored by AdventHealth Translational Research Institute.
NCT04432090 is a Phase 2 study that has completed, run by AdventHealth Translational Research Institute. The registered enrollment target is 110 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04432090, a Phase 2 study, has completed, sponsored by AdventHealth Translational Research Institute.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 110 participants
- Enrollment target
Study Summary
The purpose of this study is to test if a specific research medication could increase the response to low blood glucose in people with type 1 diabetes. The response of the body to low blood sugar will be measured in healthy people as a reference point.
Primary Outcome
Maximal glucagon concentration during insulin induced hypoglycemia. This was measured during the hypoglycemic steady state of the hyper-insulinemic euglycemic-hypoglycemic clamp study.
Interventions
- DRUG Placebo
- DRUG Study Medication (MBX-2982)
- OTHER No medication for this group
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2021-04-21 |
| Est. Completion | 2023-08-12 |
| Phase | Phase 2 |
What the finished NCT04432090 record still lists
NCT04432090 is an interventional study that assigns participants to a tested intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (17% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT04432090 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04432090 about?
NCT04432090 is a clinical study titled "GPR119 Agonist for Hypoglycemia in Type 1 Diabetes". The purpose of this study is to test if a specific research medication could increase the response to low blood glucose in people with type 1 diabetes. The response of the body to low blood sugar will be measured in healthy people as a reference point.
What is the current status of trial NCT04432090?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 110 participants. The study started on 2021-04-21. Estimated completion is 2023-08-12.
What interventions are being tested in trial NCT04432090?
The interventions under investigation include: Placebo (DRUG), Study Medication (MBX-2982) (DRUG), No medication for this group (OTHER).
Who is sponsoring clinical trial NCT04432090?
This trial is sponsored by AdventHealth Translational Research Institute, which has 54 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04432090's enrollment target sits among peer trials
110 632nd of 2000 higher than 1,361 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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