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NCT04422990 · ClinicalTrials.gov registry record · NA

Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens

A NA study, sponsored by Alcon Research.

Completed
Registry status
NA
Development phase
158
Enrollment target

NCT04422990: Completed NA study, sponsored by Alcon Research.

NCT04422990 is a NA study that has completed, run by Alcon Research. The registered enrollment target is 158 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04422990, a NA study, has completed, sponsored by Alcon Research.

COMPLETED
Registry status
NA
Development phase
158 participants
Enrollment target

Study Summary

The purpose of this clinical study is to evaluate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in a daily wear modality.

Primary Outcome

Visual acuity (VA) was assessed for each eye individually with study lenses in place using a letter chart. VA was collected in Snellen and converted to logarithm minimum angle of resolution (logMAR). A logMAR value of 0 equates to 20/20 Snellen visual acuity (normal distance eyesight), with lower logMAR values indicating better visual acuity.

Interventions

  • DEVICE Comfilcon A contact lenses
  • DEVICE Lehfilcon A contact lenses
  • DEVICE CLEAR CARE

Trial Details

FieldValue
Enrollment Target 158 participants
Start Date 2020-10-01
Est. Completion 2021-05-18
Phase NA
Alcon Research

275 total trials

What the finished NCT04422990 record still lists

NCT04422990 is an interventional study that assigns participants to a tested intervention. The registered 158 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower).

The record links to 0 conditions, and to 3 interventions - of which Comfilcon A contact lenses is the first listed.

NCT04422990 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04422990 about?

NCT04422990 is a clinical study titled "Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens". The purpose of this clinical study is to evaluate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in a daily wear modality.

What is the current status of trial NCT04422990?

This trial is currently completed. It is a NA study. The enrollment target is 158 participants. The study started on 2020-10-01. Estimated completion is 2021-05-18.

What interventions are being tested in trial NCT04422990?

The interventions under investigation include: Comfilcon A contact lenses (DEVICE), Lehfilcon A contact lenses (DEVICE), CLEAR CARE (DEVICE).

Who is sponsoring clinical trial NCT04422990?

This trial is sponsored by Alcon Research, which has 275 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04422990's enrollment target sits among peer trials

158 654th of 2000 higher than 1,345 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04422990, the US trial registry maintained by the National Library of Medicine. NCT04422990 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.