Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04420585 · ClinicalTrials.gov registry record · Phase 4
Desmopressin for Bedwetting in Children With SCD
A Phase 4 study, sponsored by Montefiore Medical Center.
- Terminated
- Registry status
- Phase 4
- Development phase
- 8
- Enrollment target
NCT04420585: Clinical Trial Phase 4 study, sponsored by Montefiore Medical Center.
NCT04420585 is a Phase 4 study that was terminated before completion, run by Montefiore Medical Center. The registered enrollment target is 8 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04420585, a Phase 4 study, was terminated before completion, sponsored by Montefiore Medical Center.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 8 participants
- Enrollment target
Study Summary
This study assesses if using the medication desmopressin will decrease nightime bedwetting in children with sickle cell disease.
Primary Outcome
Change in the percentage of nights with bedwetting episodes assessed at baseline based on participant recall over the previous 14 nights, as well as at \~1 month (30 nights) based on completion of a study (enuresis) diary. This is used to assess whether the use of desmopressin in patients with sickle cell disease and nocturnal enuresis will decrease the number of nighttime episodes of enuresis by 50% after initiating DDAVP at 0.4 mg nightly dose (with dose escalation as clinically appropriate).
Interventions
- DRUG Desmopressin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2020-07-07 |
| Est. Completion | 2023-06-12 |
| Phase | Phase 4 |
Why NCT04420585 stopped before completion
NCT04420585 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Desmopressin is the first listed.
NCT04420585 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04420585 about?
NCT04420585 is a clinical study titled "Desmopressin for Bedwetting in Children With SCD". This study assesses if using the medication desmopressin will decrease nightime bedwetting in children with sickle cell disease.
What is the current status of trial NCT04420585?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 8 participants. The study started on 2020-07-07. Estimated completion is 2023-06-12.
What interventions are being tested in trial NCT04420585?
The interventions under investigation include: Desmopressin (DRUG).
Who is sponsoring clinical trial NCT04420585?
This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04420585's enrollment target sits among peer trials
8 1972nd of 2000 higher than 20 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI