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NCT04418297 · ClinicalTrials.gov registry record · Phase 1
A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CT-G20 in Subjects With Obstructive Hypertrophic Cardiomyopathy
A Phase 1 study, sponsored by Celltrion.
- Terminated
- Registry status
- Phase 1
- Development phase
- 23
- Enrollment target
NCT04418297: Clinical Trial Phase 1 study, sponsored by Celltrion.
NCT04418297 is a Phase 1 study that was terminated before completion, run by Celltrion. The registered enrollment target is 23 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04418297, a Phase 1 study, was terminated before completion, sponsored by Celltrion.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 23 participants
- Enrollment target
Study Summary
This is a randomized, double-blind, placebo-controlled, sequential, 5-day treatment, ascending dose study in subjects with obstructive HCM aged 18-70 years. The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of CT-G20.
Interventions
- DRUG Placebo
- DRUG CT-G20
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2020-10-23 |
| Est. Completion | 2022-11-22 |
| Phase | Phase 1 |
Why NCT04418297 stopped before completion
NCT04418297 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04418297 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04418297 about?
NCT04418297 is a clinical study titled "A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CT-G20 in Subjects With Obstructive Hypertrophic Cardiomyopathy". This is a randomized, double-blind, placebo-controlled, sequential, 5-day treatment, ascending dose study in subjects with obstructive HCM aged 18-70 years. The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of CT-G20.
What is the current status of trial NCT04418297?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2020-10-23. Estimated completion is 2022-11-22.
What interventions are being tested in trial NCT04418297?
The interventions under investigation include: Placebo (DRUG), CT-G20 (DRUG).
Who is sponsoring clinical trial NCT04418297?
This trial is sponsored by Celltrion, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04418297's enrollment target sits among peer trials
23 1596th of 2000 higher than 400 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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